In search of new anticancer drugs: Data for cytotoxic activities of green synthesized silver nanoparticles from ethanolic extracts of fruits and leaves of Annona muricata and 5- Fluorouracil against HeLa, PC3 and PNT1A cell lines

Simple item page
dc.contributor.authorGavamukulya, Yahaya
dc.contributor.authorMaina, Esther N.
dc.contributor.authorMeroka, Amos M.
dc.contributor.authorEl-Shemy, Hany A.
dc.contributor.authorMagoma, Gabriel
dc.contributor.authorWamunyokoli, Fred
dc.date.accessioned2023-01-30T18:35:37Z
dc.date.available2023-01-30T18:35:37Z
dc.date.issued2019
dc.description.abstractIn this article, we present data on the anticancer activities of green synthesized silver nanoparticles (AgNPs) from ethanolic extracts of fruits (AgNPs-F) and leaves (AgNPs-L) of Annona muricata and standard anticancer drug 5-Fluorouracil (5-FU) on two cancer cell lines, i.e. cervical adenocarcinoma (HeLa cells) and prostate adenocarcinoma (PC3 cells) as well as on an immortalized normal prostate cell line, PNT1A. The cytotoxicity on the cells was determined by measuring the absorbance signal of resazurin dye. It has long been known that metabolically active cells change the resazurin from blue (oxidized) to red (reduced) forms, corresponding to the absorbance signals at a wavelength of 570nm (A570) and 600nm (A600) respectively, from which therefore the effects of any treatments on percentage cell viability/death can be elucidated. The raw data values of the treatments against the HeLa, PC3 and PNT1A cells are shown in the different Tables. Examples of how the data can be analyzed have been illustrated using different growth inhibition curves. The data can be used by academics, students, and researchers working on development of anticancer drugs.en_US
dc.identifier.citationGavamukulya, Y., Maina, E. N., Meroka, A. M., El-Shemy, H. A., Magoma, G., & Wamunyokoli, F. (2019). In search of new anticancer drugs: Data for cytotoxic activities of green synthesized silver nanoparticles from ethanolic extracts of fruits and leaves of Annona muricata and 5-Fluorouracil against HeLa, PC3 and PNT1A cell lines. Data in brief, 26, 104442. https://doi.org/10.1016/j.dib.2019.104442en_US
dc.identifier.urihttps://doi.org/10.1016/j.dib.2019.104442
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7403
dc.language.isoenen_US
dc.publisherData in briefen_US
dc.subjectSilver nanoparticles (AgNPs)en_US
dc.subject5FUen_US
dc.titleIn search of new anticancer drugs: Data for cytotoxic activities of green synthesized silver nanoparticles from ethanolic extracts of fruits and leaves of Annona muricata and 5- Fluorouracil against HeLa, PC3 and PNT1A cell linesen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
In search of new anticancer drugs Data for.pdf
Size:
714.84 KB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Engineering and Technology