The National Research Repository of Uganda - NRU

Welcome to the National Research Repository of Uganda, abbreviated as "NRU". NRU was established in 2021. NRU is a collection of scholarly output by researchers from the UNCST Community, including scholarly articles and books, electronic theses and dissertations, conference proceedings, journals, technical reports and digitised library collections. It is the official Institutional Archive (IA) of UNCST.

Copyright Information:

For information about the publishers' copyright policy on archiving your articles online or in an institutional archive, visit the Sherpa Site at http://www.sherpa.ac.uk/romeo.php The site gives a summary of the permissions normally given as part of each publisher's copyright transfer agreement. If you wish to publish your research findings in the NRU, please contact NRU administrator at admin@uncst.go.ug for details. NRU operates both open access and closed access models. Access to fulltext has been restricted in adherence to the UNCST Intellectual Property Rights (IPR) and Copyrights policies.

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Africa Portal is an online repository of open access library collection with over 3,000 books, journals, and digital documents on African policy issues. This is an initiative by the Centre for International Governance Innovation (CIGI), Makerere University (MAK), and the South African Institute of International Affairs (SAIIA). Please visit the Africa Portal at http://www.africaportal.org/library.

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Recent Submissions

  • Item type:Item,
    12th ANREC proceedings (full report)
    (Uganda National Council for Science and Technology, 2025-10-20)
    Uganda National Council for Science and Technology
    These proceedings document presentations, panel discussions, keynote addresses, case studies, and stakeholder engagements from the 12th Annual National Research Ethics Conference (ANREC), held on 21-22 October 2025 in Kampala, Uganda. The conference explored the theme "Communities as Partners: Strengthening Community Engagement in Research" and examined ethical, regulatory, and practical dimensions of community participation in research. Key discussions addressed evolving global and national research ethics frameworks, updates to the Declaration of Helsinki, revised Ugandan research guidelines, post-research responsibilities, ethical challenges in controlled human infection studies, adaptive trial designs, emergency and outbreak research, animal welfare, traditional and alternative medicine research, gene therapy, artificial intelligence, data ownership, and intellectual property rights. Participants emphasized the importance of collaborative partnerships between researchers and communities, equitable benefit-sharing, inclusive research governance, culturally responsive research methods, and accountability throughout the research lifecycle. The proceedings further highlight lessons learned from community engagement initiatives, vaccine trials, public health emergencies, and emerging research technologies, while providing recommendations for strengthening ethical oversight, participant protection, and sustainable research systems in Uganda and the region.
  • Item type:Item,
    12th ANREC proceedings (summary)
    (Uganda National Council for Science and Technology, 2025-10-21)
    Uganda National Council for Science and Technology
    .The 12th Annual National Research Ethics Conference (ANREC), organized by the Uganda National Council for Science and Technology (UNCST), was held on 21-22 October 2025 in Kampala, Uganda, under the theme "Communities as Partners: Strengthening Community Engagement in Research." The conference brought together 706 participants from Uganda and the region to discuss contemporary ethical issues in human and animal research. Deliberations emphasized community engagement as a fundamental pillar of ethical, inclusive, and responsive research, advocating a shift from conducting research on communities to conducting research with communities. Major discussions focused on post-research responsibilities, post-trial access, ethical challenges in emergency and outbreak research, social and behavioral research ethics, traditional and alternative medicine research, animal welfare, emerging technologies, adaptive clinical trial designs, and community-centered research governance. The conference highlighted the need for meaningful community participation throughout the research lifecycle, strengthened ethical and regulatory frameworks, equitable benefit-sharing, accountability in dissemination of research findings, and alignment with the revised Declaration of Helsinki. Recommendations called for institutionalizing community engagement, strengthening post-research obligations, enhancing ethical oversight, promoting indigenous knowledge systems, and advancing equitable research partnerships to improve research quality, trust, and public benefi
  • Item type:Item,
    Implementing an intra outbreak ring vaccination clinical trial for Sudan Ebola virus disease within four days of outbreak notification in Uganda
    (Taylor & Francis Group, 2026-09-16)
    Winters Muttamba;
    ;
    Henry Kyobe Bosa;
    ;
    Misaki Wayengera ;
    ;
    Andrew Obuku;
    ;
    Maria Sekimpi;
    East and Central Africa experiences heightened threats for Ebola Virus Disease (EVD), with the latest outbreak caused by the Bundibugyo ebolavirus (BDBV) reported in the Democratic Republic of the Congo (DRC) and Uganda on 15th May 2026. The BDBV outbreak comes just over a year following declaration of Sudan Virus Disease (SVD) outbreak in Uganda on 30th January 2025. Following the 2025 outbreak, a race against the clock mobilisation occurred over the subsequent four days to launch a ring vaccination trial for a candidate vaccine against SVD. During this four-day period, the investigation team leveraged ongoing engagements with trial sponsors to activate prefinancing mechanisms and unlock in-kind financing from the government of Uganda. Further, the team activated a prepositioned research protocol to secure rapid ethics and regulatory clearance, and quickly accessed investigation product within the country, supportive ethics/regulatory systems, presence of logistical and data management systems established during the 2022 outbreak, collaborative relationship between the trial and the Ministry of Health outbreak response teams. Finally, previously trained field and community engagement personnel were mobilised overnight, offered refresher training and rapidly deployed to the field. In conclusion, the unprecedented four-day turnaround was made possible by the research, logistical and staffing capacities established during the 2022 SVD outbreak, an achievement that offers a blueprint for rapid evaluation of medical countermeasures during outbreaks.
  • Item type:Item,
    Community event-based surveillance as trust infrastructure for Bundibugyo Ebola response
    (Elsevier Ltd, 2026-09-08)
    Baker, Pieter
    The 2026 outbreak of Ebola caused by Bundibugyo virus disease in the Democratic Republic of the Congo and Uganda highlights persistent gaps in centralized outbreak surveillance, particularly in settings affected by insecurity, displacement, cross-border mobility, community mistrust, and limited disease-specific countermeasures. Community event-based surveillance (CEBS) offers a practical approach for strengthening case-finding while building trust. CEBS relies on trained, equipped, and compensated community members to report trigger events that may indicate hidden transmission, linking local alerts to rapid verification, referral, household support, and formal outbreak response. Sierra Leone's experience during the 2014-16 West African Ebola epidemic provides an important model: CEBS was piloted in Bo District and later scaled through the Ebola Response Consortium, generating alerts that contributed to detection of confirmed Ebola cases, including cases with no known epidemiological link at detection. For the current Bundibugyo outbreak, CEBS should be adapted as a locally governed extension of health-zone and district surveillance structures. Funded well, CEBS can improve timely detection, link households to care, reinforce community trust and strengthen preparedness beyond a single outbreak.The 2026 outbreak of Ebola caused by Bundibugyo virus disease in the Democratic Republic of the Congo and Uganda highlights persistent gaps in centralized outbreak surveillance, particularly in settings affected by insecurity, displacement, cross-border mobility, community mistrust, and limited disease-specific countermeasures. Community event-based surveillance (CEBS) offers a practical approach for strengthening case-finding while building trust. CEBS relies on trained, equipped, and compensated community members to report trigger events that may indicate hidden transmission, linking local alerts to rapid verification, referral, household support, and formal outbreak response. Sierra Leone's experience during the 2014-16 West African Ebola epidemic provides an important model: CEBS was piloted in Bo District and later scaled through the Ebola Response Consortium, generating alerts that contributed to detection of confirmed Ebola cases, including cases with no known epidemiological link at detection. For the current Bundibugyo outbreak, CEBS should be adapted as a locally governed extension of health-zone and district surveillance structures. Funded well, CEBS can improve timely detection, link households to care, reinforce community trust and strengthen preparedness beyond a single outbreak.
  • Item type:Item,
    Prevalence and factors associated with experiencing occupational biological hazards among clinical university students in South Western Uganda
    (BioMed Central, 2026-09-04)
    Ayesiga, Innocent;
    ;
    Wekha, Godfrey;
    ;
    Kihumuro, Raymond Bernard ;
    ;
    Nakandi, Racheal Mukisa;
    ;
    Tenywa, David;
    BackgroundClinical students face hazards, such as needlestick injuries and blood spills. While healthcare workers’ exposure to such hazards is well-documented, there is limited data on medical students, particularly in Uganda. We explored the prevalence and factors associated with biological occupational hazards among clinical university students.MethodsThis cross-sectional study examined biological occupational hazards among 384 randomly selected undergraduate clinical medical students at a university in Southwestern Uganda. Data were collected using a structured self-administered questionnaire. Categorical and numerical data were summarised descriptively using frequencies and means. Multivariable logistic regression identified factors independently associated with hazard exposure. Adjusted odds ratios with 95% confidence intervals were reported, and a p < 0.05 was considered statistically significant.ResultsA total of 384 participants, with a mean age of 25.1 years and a male predominance of 208 (54.2%), were included; 223 (58.1%) pursued careers in medicine and surgery. 316 (82.3%) reported experiencing a hazard, with 107 (33.9%) reporting experiencing it more than three times. 155 (49.1%) and 102 (32.3%) of the participants had experienced blood spills and needle stick injuries, respectively. Gender (aOR 0.448, CI: 0.24–0.84) and the current ward where the students were placed (aOR 2.94, CI: 1.39–6.22) were significantly associated with exposure to hazards.ConclusionClinical students are significantly exposed to occupational hazards, with blood spills and needle stick injuries being the most common. Most students experience multiple exposures in high-risk wards such as Obstetrics. Targeted interventions, such as establishing injury response teams, pinning procedure charts on the ward walls, and providing procedure manuals, are needed to enhance safety and improve clinical training. Future research should also examine safety protocols and gendered risk perceptions to develop effective strategies to mitigate hazards. Health & Medical Collection (Module)