Antibacterial Activity of Carica papaya against Methicillin resistant Staphylococcus epidermidis Isolated from Wards Surfaces of Kampala International University Teaching Hospital, Bushenyi, Uganda

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dc.contributor.authorSunusi Adam, Abubakar
dc.contributor.authorNtulume, Ibrahim
dc.contributor.authorAdeyemo, Rasheed
dc.contributor.authorAkinola, Saheed
dc.contributor.authorJatau Abubakar, Ibrahim
dc.contributor.authorAlmustapha Aleiro, Adamu
dc.contributor.authorOnkobah, Sarah
dc.contributor.authorMicheni, Lisa
dc.contributor.authorNamatovu, Alice
dc.date.accessioned2023-01-24T16:29:16Z
dc.date.available2023-01-24T16:29:16Z
dc.date.issued2019
dc.description.abstractThis study aimed at determining the antibacterial activity of Carica papaya against Methicillin resistant Staphylococcus epidermidis isolated from doorknobs, bed rails, floors and walls of Surgical, Medical, Maternity, Pediatrics, Accident and Emergency, Semiprivate and Private wards of Kampala International University Teaching Hospital. The bacteria were isolated from the wards surfaces and identified using biochemical tests, Desferroxiomine and Fosfomycin antibiotics. Disc diffusion method was used to detect methicillin resistance in S. epidermidis using Cefoxitin (30 μg) disc. Fresh leaves and seeds of C. papaya was processed and extracted using standard methods. Antibacterial activities of the methanol, acetone and aqueous crude extracts were assayed using the agar well diffusion method. Phytochemical analysis, Minimum Inhibitory and Bactericidal concentration of the crude extracts were determined using broth dilution methods. Both C. papaya leaf and seed crude extract exhibited antibacterial activity against MRSE with MICs and MBCs ranges of 250 to 31.3mg/ml and 125 to 31.3 mg/mL for leaf and seed extracts respectively. This study concludes that C. papaya leaf and seed crude extracts were effective against Methicillin resistant S. epidermidis.en_US
dc.identifier.citationAdam, A. S., Ntulume, I., Adeyemo, R., Akinola, S., Abubakar, I. J., Aleiro, A. A., ... & Namatovu, A. (2019). Antibacterial Activity of Carica papaya against Methicillin resistant Staphylococcus epidermidis Isolated from Wards Surfaces of Kampala International University TeachingHospital, Bushenyi, Uganda. Current Trends in Biotechnology and Pharmacy, 13(4), 391-400.en_US
dc.identifier.issn0973-8916
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7163
dc.language.isoenen_US
dc.publisherCurrent Trends in Biotechnology and Pharmacyen_US
dc.subjectAntibacterial Activityen_US
dc.subjectCarica papayaen_US
dc.subjectMethicillinen_US
dc.subjectStaphylococcus epidermidisen_US
dc.subjectKampala International University Teaching Hospitalen_US
dc.titleAntibacterial Activity of Carica papaya against Methicillin resistant Staphylococcus epidermidis Isolated from Wards Surfaces of Kampala International University Teaching Hospital, Bushenyi, Ugandaen_US
dc.typeArticleen_US
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