Browsing by Author "Okello, Innocent"

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    Burden of Emergency Pediatric Surgical Procedures on Surgical Capacity in Uganda: A New Metric for Health System Performance
    (Surgery, 2020) Grabski, David F.; Kakembo, Nasser; Situma, Martin; Cheung, Maija; Shikanda, Anne; Okello, Innocent; Kisa, Phyllis; Muzira, Arlene; Sekabira, John; Ozgediz, Doruk
    The significant burden of emergency operations in low- and middle-income countries can overwhelm surgical capacity leading to a backlog of elective surgical cases. The purpose of this investigation was to determine the burden of emergency procedures on pediatric surgical capacity in Uganda and to determine health metrics that capture surgical backlog and effective coverage of children’s surgical disease in low- and middle-income countries.We reviewed 2 independent and prospectively collected databases on pediatric surgical admissions at Mulago National Referral Hospital and Mbarara Regional Referral Hospital in Uganda. Pediatric surgical patients admitted at either hospital between October 2015 to June 2017 were included. Our primary outcome was the distribution of surgical acuity and associated mortality.A combined total of 1,930 patients were treated at the two hospitals, and 1,110 surgical procedures were performed. There were 571 emergency cases (51.6%), 108 urgent cases (9.7%), and 429 elective cases (38.6%). Overall mortality correlated with surgical acuity. Emergency intestinal diversions for colorectal congenital malformations (anorectal malformations and Hirschsprung’s disease) to elective definitive repair was 3:1. Additionally, 30% of inguinal hernias were incarcerated or strangulated at time of repair.Emergency and urgent operations utilize the majority of operative resources for pediatric surgery groups in low- and middle-income countries, leading to a backlog of complex congenital procedures. We propose the ratio of emergency diversion to elective repair of colorectal congenital malformations and the ratio of emergency to elective repair of inguinal hernias as effective health metrics to track this backlog. Surgical capacity for pediatric conditions should be increased in Uganda to prevent a backlog of elective cases.
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    Implementation of a Contextually Appropriate Pediatric Emergency Surgical Care Course in Uganda
    (Journal of Pediatric Surgery, 2021) Ullrich, Sarah; Kisa, Phyllis; Ruzgar, Nensi; Okello, Innocent; Oyania, Felix; Kayima, Peter; Kakembo, Nasser; Sekabira, John; Situma, Martin; Ozgediz, Doruk
    Low- and middle-income countries like Uganda face a severe shortage of pediatric surgeons. Most children with a surgical emergency are treated by nonspecialist rural providers. We describe the design and implementation of a locally driven, pilot pediatric emergency surgical care course to strengthen skills of these providers. This is the first description of such a course in the current literature.The course was delivered three times from 2018 to 2019. Modules include perioperative management, neonatal emergencies, intestinal emergencies, and trauma. A baseline needs assessment survey was administered. Participants in the second and third courses also took pre and postcourse knowledge-based tests.Forty-five providers representing multiple cadres participated. Participants most commonly perform hernia/hydrocele repair (17% adjusted rating) in their current practice and are least comfortable managing cleft lip and palate (mean Likert score 1.4 ± 0.9). Equipment shortage was identified as the most significant challenge to delivering pediatric surgical care (24%). Scores on the knowledge tests improved significantly from pre- (55.4% ± 22.4%) to postcourse (71.9% ± 14.0%, p < 0.0001).Nonspecialist clinicians are essential to the pediatric surgical workforce in LMICs. Short, targeted training courses can increase provider knowledge about the management of surgical emergencies. The course has spurred local surgical outreach initiatives. Further implementation studies are needed to evaluate the impact of the training.
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    Pyloric Stenosis at a Tertiary Hospital in Uganda
    (Annals of Pediatric Surgery, 2020) Okello, Innocent; Naluyimbazi, Rovine; Massenga, Alicia; Ullrich, Sarah; Kakembo, Nasser; Kisa, Phyllis; Sekabira, John; Nimanya, Stella
    Worldwide, infantile hypertrophic pyloric stenosis has an incidence of 3 in 1000 livebirths, with an unknown etiology. Even when babies present with characteristic symptoms, it is often misdiagnosed leading to late referral for appropriate surgical care. The purpose of this study was to document our experience in management of pyloric stenosis within our setting.A total of 33 patient records were reviewed. All the patients presented with non-bilious vomiting. The ratio of males to females was 4.5:1. Of these patients, 76% had electrolyte imbalance with low chloride count in the majority of patients. All the patients underwent an open Ramstedt pyloromyotomy, and 91% had a good outcome.Management of IHPS has very good outcomes in our setting. Earlier referral of patients leads to improved outcomes.
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    Unifying Children’s Surgery and Anesthesia Stakeholders Across Institutions and Clinical Disciplines: Challenges and Solutions from Uganda
    (World Journal of Surgery, 2019) Kisa, Phyllis; Ajiko, Margaret; Male, Doreen Birabwa; Galiwango, George; Kakembo, Nasser; Kambugu, Joyce B.; Muhumuza, Moses Fisha; Muzira, Arlene; Nabukenya, Mary T.; Nakku, Doreen; Nankunda, Jolly; Ogwang, Martin; Okello, Innocent; Ssenyonga, Peter; Tumukunde, Janat
    There is a significant unmet need for children’s surgical care in low- and middle-income countries (LMICs). Multidisciplinary collaboration is required to advance the surgical and anesthesia care of children’s surgical conditions such as congenital conditions, cancer and injuries. Nonetheless, there are limited examples of this process from LMICs. We describe the development and 3-year outcomes following a 2015 stakeholders’ meeting in Uganda to catalyze multidisciplinary and multi-institutional collaboration. The stakeholders’ meeting was a daylong conference held in Kampala with local, regional and international collaborators in attendance. Multiple clinical specialties including surgical subspecialists, pediatric anesthesia, perioperative nursing, pediatric oncology and neonatology were represented. Key thematic areas including infrastructure, training and workforce retention, service delivery, and research and advocacy were addressed, and short-term objectives were agreed upon. We reported the 3-year outcomes following the meeting by thematic area. The Pediatric Surgical Foundation was developed following the meeting to formalize coordination between institutions. Through international collaborations, operating room capacity has increased. A pediatric general surgery fellowship has expanded at Mulago and Mbarara hospitals supplemented by an international fellowship in multiple disciplines. Coordinated outreach camps have continued to assist with training and service delivery in rural regional hospitals. Collaborations between disciplines, both within LMICs and with international partners, are required to advance children’s surgery. The unification of stakeholders across clinical disciplines and institutional partnerships can facilitate increased children’s surgical capacity. Such a process may prove useful in other LMICs with a wide range of children’s surgery stakeholders.
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    Urinary Bladder Rupture in an 18-Day-Old Boy Following Circumcision at a Health Centre in Uganda
    (East and Central African Journal of Surgery, 2020) Okello, Innocent; Kisa, Phyllis; Kakembo, Nasser; Ozgediz, Doruk; Sekabira, John
    An 18-day-old boy with a recent history of circumcision presented with abdominal swelling and inability to pass urine. Physical examination revealed abdominal distension with a firm penile dressing. The diagnosis of peritonitis was made, and urinary bladder rupture with ascites was found at laparotomy. He had a smooth postoperative recovery and was discharged on the seventh postoperative day. At follow up one month post-surgery, he is well with good bladder function and no evidence of a urethral stricture. Urinary bladder rupture is an extremely rare complication of circumcision, in this case possibly due to an occlusive dressing. Early identification is key to good prognosis of such patients