An Observational Study in an Urban Ugandan Clinic comparing Virological Outcomes of Patients Switched from first-line Antiretroviral Regimens to Second-line Regimens containing Ritonavir-boosted Atazanavir or Ritonavir-boosted Lopinavir
dc.contributor.author | Laker, Eva Agnes Odongpiny | |
dc.contributor.author | Nabaggala, Maria Sarah | |
dc.contributor.author | Kaimal, Arvind | |
dc.contributor.author | Nalwanga, Damalie | |
dc.contributor.author | Abdu Musubire, Abdu Musubire | |
dc.contributor.author | Kiragga, Agnes | |
dc.contributor.author | Lamorde, Mohammed | |
dc.contributor.author | Parkes- Ratanshi, Rosalind | |
dc.date.accessioned | 2023-06-28T15:38:10Z | |
dc.date.available | 2023-06-28T15:38:10Z | |
dc.date.issued | 2019 | |
dc.description.abstract | The World Health Organisation approved boosted atazanavir as a preferred second line protease inhibitor in 2010. This is as an alternative to the current boosted lopinavir. Atazanavir has a lower genetic barrier than lopinavir. We compared the virological outcomes of patients during the roll out of routine viral load monitoring, who had switched to boosted second- line regimens of either atazanavir or lopinavir. | en_US |
dc.identifier.citation | Laker, E. A. O., Nabaggala, M. S., Kaimal, A., Nalwanga, D., Castelnuovo, B., Musubire, A., ... & Ratanshi, R. P. (2019). An observational study in an urban Ugandan clinic comparing virological outcomes of patients switched from first-line antiretroviral regimens to second-line regimens containing ritonavir-boosted atazanavir or ritonavir-boosted lopinavir. BMC Infectious Diseases, 19(1), 1-7.https://doi.org/10.1186/s12879-019-3907-5 | en_US |
dc.identifier.issn | 1471-2334 | |
dc.identifier.uri | https://nru.uncst.go.ug/handle/123456789/9019 | |
dc.language.iso | en | en_US |
dc.publisher | BMC Infectious Diseases | en_US |
dc.subject | Lopinavir | en_US |
dc.subject | Second-line antiretroviral | en_US |
dc.subject | Atazanavir | en_US |
dc.subject | First-line failure | en_US |
dc.title | An Observational Study in an Urban Ugandan Clinic comparing Virological Outcomes of Patients Switched from first-line Antiretroviral Regimens to Second-line Regimens containing Ritonavir-boosted Atazanavir or Ritonavir-boosted Lopinavir | en_US |
dc.type | Article | en_US |
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