Clinical Characteristics and Short-Term Outcomes of HIV Patients Admitted to an African Intensive Care Unit

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dc.contributor.authorKwizera, Arthur
dc.contributor.authorNabukenya, Mary
dc.contributor.authorAgaba, Peter
dc.contributor.authorSemogerere, Lameck
dc.contributor.authorAyebale, Emmanuel
dc.contributor.authorKatabira, Catherine
dc.contributor.authorKizito, Samuel
dc.contributor.authorNantume, Cecilia
dc.contributor.authorClarke, Ian
dc.contributor.authorNakibuuka, Jane
dc.date.accessioned2023-04-28T11:32:43Z
dc.date.available2023-04-28T11:32:43Z
dc.date.issued2016
dc.description.abstractIn high-income countries, improved survival has been documented among intensive care unit (ICU) patients infected with human immune deficiency virus (HIV). There are no data from low-income country ICUs. We sought to identify clinical characteristics and survival outcomes among HIV patients in a low-income country ICU. Materials and Methods. A retrospective cohort study of HIV infected patients admitted to a university teaching hospital ICU in Uganda. Medical records were reviewed. Primary outcome was survival to hospital discharge. Statistical significance was predetermined in reference to . Results. There were 101 HIV patients. Average length of ICU stay was 4 days and ICU mortality was 57%. Mortality in non-HIV patients was 28%. Commonest admission diagnoses were Acute Respiratory Distress Syndrome (ARDS) (58.4%), multiorgan failure (20.8%), and sepsis (20.8%). The mean Acute Physiologic and Chronic Health Evaluation (APACHE II) score was 24. At multivariate analysis, APACHE II (OR 1.24 (95% CI: 1.1–1.4, )), mechanical ventilation (OR 1.14 (95% CI: 0.09–0.76, )), and ARDS (OR 4.5 (95% CI: 1.07–16.7, )) had a statistically significant association with mortality. Conclusion. ICU mortality of HIV patients is higher than in higher income settings and the non-HIV population. ARDS, APACHE II, and need for mechanical ventilation are significantly associated with mortality.en_US
dc.identifier.citationKwizera, A., Nabukenya, M., Peter, A., Semogerere, L., Ayebale, E., Katabira, C., ... & Nakibuuka, J. (2016). Clinical characteristics and short-term outcomes of HIV patients admitted to an African intensive care unit. Critical care research and practice, 2016.https://doi.org/10.1155/2016/2610873en_US
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8572
dc.language.isoenen_US
dc.publisherCritical care research and practiceen_US
dc.subjectIntensive Care Uniten_US
dc.subjectHIV Patientsen_US
dc.subjectClinical Characteristicsen_US
dc.titleClinical Characteristics and Short-Term Outcomes of HIV Patients Admitted to an African Intensive Care Uniten_US
dc.typeArticleen_US
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