Neuron-based sensors for biochemical quantitation
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Proceedings of the Annual International Engineering in Medicine and Biology Society
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Abstract
Using intracellular recording from freshly dissected Limnea stagnalis neurons and cultured clones for mouse neuroblastoma, N-18 and N1E-115, linear relationships between several analyte concentrations and neuron electrical properties, such as action potential, are obtained. This demonstrates the suitability of neurons as primary transducers in neuron-based sensors. Initial development work that will lead to testing cultured neurons for the detection of monoclonal antibodies is reported.<>
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Kisaalita, W. S., Skeen, R. S., Van Wie, B. J., Barnes, C. D., Fung, S. J., & Davis, W. C. (1989, November). Neuron-based sensors for biochemical quantitation. In Images of the Twenty-First Century.DOI: 10.1109/IEMBS.1989.96118 Proceedings of the Annual International Engineering in Medicine and Biology Society, (pp. 1124-1125). IEEE.