Prevalence of brucellosis among patients attending Wau Hospital, South Sudan

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dc.contributor.authorMadut, Nuol Aywel
dc.contributor.authorNasinyama, George William
dc.contributor.authorBwalya Muma, John
dc.contributor.authorSube, Kenneth L. L.
dc.contributor.authorOcan, Moses
dc.contributor.authorMuwonge, Adrian
dc.contributor.authorGodfroid, Jacques
dc.contributor.authorSamuel Jubara, Ambrose
dc.contributor.authorKankya, Clovice
dc.date.accessioned2022-08-15T20:45:25Z
dc.date.available2022-08-15T20:45:25Z
dc.date.issued2018
dc.description.abstractBrucellosis is a zoonotic disease of public health importance; its prevalence varies globally. In low-income countries, brucellosis is an endemic and neglected disease affecting both animals and humans. This study was intended to establish brucellosis sero-prevalence among patients attending Wau hospital, South Sudan. Across sectional study, was done among randomly selected patients attending Wau hospital. Data was collected using questionnaires and laboratory investigations. Rose Bengal plate Test (RBPT), Serum agglutination test (SAT) and Competitive Enzyme Linked Immuno Sorbent Assay (c-ELISA) was used in the analysis of blood samples serially starting with RBPT which is more sensitive and least specific then SAT. c-ELISA test which is most specific and less sensitive compared to RBPT and SAT was then used to confirm presence of Brucella antibodies in the samples. A total of 416 participants out of 1664 were enrolled to this study. The majority of participants were between 7-to-76 years of age with mean age of 30.72 (SD+/- 12.83). The sero-positivity of patient's blood samples for brucellosis using c-ELISA was 23.3% (97/416) among patients presenting to Wau hospital. Socio-demographic characteristics, occupation, clinical signs of disease and types of animals reared by animal owners showed no significant correlation with occurrence of sero-positivity among patient's blood samples for brucellosis. While ethnicity (Nilotic), knowledge of zoonotic disease, and consumption of animal urine were statistically significant (p<0.05). The study found a high prevalence of brucellosis among febrile patients attending Wau hospital general outpatient clinic. There is need for co-ordination and collaboration between veterinary and health sectors of government to help prevent and control brucellosis in the region.en_US
dc.identifier.citationMadut NA, Nasinyama GW, Muma JB, Sube KLL, Ocan M, Muwonge A, et al. (2018) Prevalence of brucellosis among patients attending Wau Hospital, South Sudan. PLoS ONE 13(6): e0199315. https://doi.org/10.1371/journal. pone.0199315en_US
dc.identifier.urihttps://doi.org/10.1371/journal. pone.0199315
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/4276
dc.language.isoenen_US
dc.publisherPloS oneen_US
dc.subjectBrucellosisen_US
dc.subjectPatientsen_US
dc.subjectWau Hospitalen_US
dc.subjectSouth Sudanen_US
dc.titlePrevalence of brucellosis among patients attending Wau Hospital, South Sudanen_US
dc.typeArticleen_US
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