Towards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisis

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dc.contributor.authorMatovu, Enock
dc.contributor.authorKazibwe, Anne Juliet
dc.contributor.authorMugasa, Claire Mack
dc.contributor.authorNdungu, Joseph Mathu
dc.contributor.authorKithingi Njiru, Zablon
dc.date.accessioned2022-11-23T12:21:23Z
dc.date.available2022-11-23T12:21:23Z
dc.date.issued2012
dc.description.abstractHuman African trypanosomiasis is a debilitating disease prevalent in rural sub-Saharan Africa. Control of this disease almost exclusively relies on chemotherapy that should be driven by accurate diagnosis, given the unacceptable toxicity of the few available drugs. Unfortunately, the available diagnostics are characterised by low sensitivities due to the inherent low parasitaemia in natural infections. Demonstration of the trypanosomes in body fluids, which is a prerequisite before treatment, often follows complex algorithms. In this paper, we review the available diagnostics and explore recent advances towards development of novel point-ofcare diagnostic tests.en_US
dc.identifier.citationMatovu, E., Kazibwe, A. J., Mugasa, C. M., Ndungu, J. M., & Njiru, Z. K. (2012). Towards point-of-care diagnostic and staging tools for human African trypanosomiaisis. Journal of tropical medicine, 2012. doi:10.1155/2012/340538en_US
dc.identifier.other10.1155/2012/340538
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/5375
dc.language.isoenen_US
dc.publisherJournal of tropical medicineen_US
dc.subjectPoint-of-Care Diagnosticen_US
dc.subjectStaging Toolsen_US
dc.subjectHuman African Trypanosomiaisisen_US
dc.titleTowards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisisen_US
dc.typeArticleen_US
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