Towards Point-of-Care Diagnostic and Staging Tools for Human African Trypanosomiaisis
Loading...
Date
2012
Journal Title
Journal ISSN
Volume Title
Publisher
Journal of tropical medicine
Abstract
Human African trypanosomiasis is a debilitating disease prevalent in rural sub-Saharan Africa. Control of this disease almost
exclusively relies on chemotherapy that should be driven by accurate diagnosis, given the unacceptable toxicity of the few available
drugs. Unfortunately, the available diagnostics are characterised by low sensitivities due to the inherent low parasitaemia in natural
infections. Demonstration of the trypanosomes in body fluids, which is a prerequisite before treatment, often follows complex
algorithms. In this paper, we review the available diagnostics and explore recent advances towards development of novel point-ofcare
diagnostic tests.
Description
Keywords
Point-of-Care Diagnostic, Staging Tools, Human African Trypanosomiaisis
Citation
Matovu, E., Kazibwe, A. J., Mugasa, C. M., Ndungu, J. M., & Njiru, Z. K. (2012). Towards point-of-care diagnostic and staging tools for human African trypanosomiaisis. Journal of tropical medicine, 2012. doi:10.1155/2012/340538