Thirty-day postoperative outcome of patients with non-traumatic gastroduodenal perforations in southwestern Uganda
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Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
Tropical Doctor
Abstract
We studied our 30-day postoperative outcomes in patients with non-traumatic gastroduodenal perforation (NTGDP) in
Mbarara Regional Referral Hospital, southwestern Uganda. We conducted a one-year prospective study of patients who
underwent exploratory laparotomy for suspected NTGDP between June 2016 and July 2017. Twenty-nine patients had
NTGDP, the male-to-female ratio was 3:1 and median age was 60 years (range¼13–80 years). Most (83%) patients were
negative for Helicobacter pylori on histology. One patient had a gastric adenocarcinoma. A total of 26 (90%) patients had
Graham’s omentopexy performed. The 30-day mortality rate was 34%. Pyrexia at hospital admission, pre-surgical delay
(> 72 h), preoperative shock and peritoneal contamination, were associated with higher mortality rates with preoperative
shock being an independent predictor of mortality. H. pylori-negative NTGDP presents a unique challenge in our
setting, affecting mainly middle-aged and elderly patients. One-third of our patients did not survive one month.
Description
Keywords
Non-traumatic gastroduodenal perforation, 30-day outcome, Southwestern Uganda
Citation
Okidi, R., Sambo, V. D., Ogwang, M. D., Mutiibwa, D., Benitez, N. P., & Bongomin, F. (2020). Thirty-day postoperative outcome of patients with non-traumatic gastroduodenal perforations in southwestern Uganda. Tropical Doctor, 50(1), 15-19. DOI: 10.1177/0049475519887654