Thirty-day postoperative outcome of patients with non-traumatic gastroduodenal perforations in southwestern Uganda

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Date
2020Author
Okidi, Ronald
Sambo, Vanusa D.
Ogwang, Martin D.
Mutiibwa, David
Benitez, Noralis P.
Bongomin, Felix
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We studied our 30-day postoperative outcomes in patients with non-traumatic gastroduodenal perforation (NTGDP) in
Mbarara Regional Referral Hospital, southwestern Uganda. We conducted a one-year prospective study of patients who
underwent exploratory laparotomy for suspected NTGDP between June 2016 and July 2017. Twenty-nine patients had
NTGDP, the male-to-female ratio was 3:1 and median age was 60 years (range¼13–80 years). Most (83%) patients were
negative for Helicobacter pylori on histology. One patient had a gastric adenocarcinoma. A total of 26 (90%) patients had
Graham’s omentopexy performed. The 30-day mortality rate was 34%. Pyrexia at hospital admission, pre-surgical delay
(> 72 h), preoperative shock and peritoneal contamination, were associated with higher mortality rates with preoperative
shock being an independent predictor of mortality. H. pylori-negative NTGDP presents a unique challenge in our
setting, affecting mainly middle-aged and elderly patients. One-third of our patients did not survive one month.
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