Effect of pre-operative bicarbonate infusion on maternal and perinatal outcomes among women with obstructed labour in Mbale hospital: A double blind randomized controlled trial

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dc.contributor.authorMusaba, Milton W.
dc.contributor.authorWandabwa, Julius N.
dc.contributor.authorNdeezi, Grace
dc.contributor.authorWeeks, Andrew D.
dc.contributor.authorMukunya, David
dc.contributor.authorWaako, Paul
dc.contributor.authorNankabirwa, Victoria
dc.contributor.authorTulyamuhika Mugabe, Kenneth
dc.contributor.authorSemakula, Daniel
dc.contributor.authorTumwine, James K.
dc.contributor.authorBarageine, Justus K.
dc.date.accessioned2021-12-12T12:52:15Z
dc.date.available2021-12-12T12:52:15Z
dc.date.issued2021
dc.description.abstractOral bicarbonate solution is known to improve both maternal and perinatal outcomes among women with abnormal labor (dystocia). Its effectiveness and safety among women with obstructed labor is not known. Objective To determine the effect and safety of a single-dose preoperative infusion of sodium bicarbonate on maternal and fetal blood lactate and clinical outcomes among women with obstructed labor (OL) in Mbale hospital. Methods We conducted a double blind, randomized controlled trial from July 2018 to September 2019. The participants were women with OL at term (�37 weeks gestation), carrying a singleton pregnancy with no other obstetric emergency, medical comorbidity or laboratory derangements.en_US
dc.identifier.citationMusaba MW, Wandabwa JN, Ndeezi G, Weeks AD, Mukunya D, Waako P, et al. (2021) Effect of pre-operative bicarbonate infusion on maternal and perinatal outcomes among women with obstructed labour in Mbale hospital: A double blind randomized controlled trial. PLoS ONE 16(2): e0245989. https://doi.org/10.1371/journal. pone.0245989en_US
dc.identifier.urihttps://doi.org/10.1371/journal. pone.0245989
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/350
dc.language.isoenen_US
dc.publisherPLoS ONEen_US
dc.subjectBicarbonate infusionen_US
dc.subjectMaternalen_US
dc.subjectPerinatal outcomesen_US
dc.subjectWomenen_US
dc.subjectLaboren_US
dc.subjectMbale hospitalen_US
dc.titleEffect of pre-operative bicarbonate infusion on maternal and perinatal outcomes among women with obstructed labour in Mbale hospital: A double blind randomized controlled trialen_US
dc.typeArticleen_US
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