Effect of pre-operative bicarbonate infusion on maternal and perinatal outcomes among women with obstructed labour in Mbale hospital: A double blind randomized controlled trial
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
PLoS ONE
Abstract
Oral bicarbonate solution is known to improve both maternal and perinatal outcomes among women with abnormal labor (dystocia). Its effectiveness and safety among women with obstructed labor is not known.
Objective
To determine the effect and safety of a single-dose preoperative infusion of sodium bicarbonate
on maternal and fetal blood lactate and clinical outcomes among women with obstructed labor (OL) in Mbale hospital.
Methods
We conducted a double blind, randomized controlled trial from July 2018 to September 2019. The participants were women with OL at term (�37 weeks gestation), carrying a singleton pregnancy with no other obstetric emergency, medical comorbidity or laboratory derangements.
Description
Keywords
Bicarbonate infusion, Maternal, Perinatal outcomes, Women, Labor, Mbale hospital
Citation
Musaba MW, Wandabwa JN, Ndeezi G, Weeks AD, Mukunya D, Waako P, et al. (2021) Effect of pre-operative bicarbonate infusion on maternal and perinatal outcomes among women with obstructed labour in Mbale hospital: A double blind randomized controlled trial. PLoS ONE 16(2): e0245989. https://doi.org/10.1371/journal. pone.0245989