Perinatal HIV Status and Executive Function During School-Age and Adolescence

Abstract
The aim of this study was to determine whether perinatal HIV infection (PHIV), HIV-exposed uninfected (PHEU) versus HIVunexposed (PHU) status predicted long-term executive function (EF) deficit in school-aged Ugandan children. Perinatal HIV status was determined by 18 months via DNA polymerase chain reaction test and confirmed at cognitive assessment between 6 and 18 years using HIV rapid-diagnostic test. Primary outcome is child EF measured using behavior-rating inventory of executive function questionnaire across 8 subscales summed to derive the global executive composite (GEC).
Description
Keywords
HIV, School-Age, Adolescence
Citation
Ezeamama, A. E., Kizza, F. N., Zalwango, S. K., Nkwata, A. K., Zhang, M., Rivera, M. L., ... & Whalen, C. C. (2016). Perinatal HIV status and executive function during school-age and adolescence: a comparative study of long-term cognitive capacity among children from a high HIV prevalence setting. Medicine, 95(17). DOI: 10.1097/MD.0000000000003438