Asymptomatic bacteriuria among pregnant women attending antenatal care at Mbale Hospital, Eastern Uganda

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dc.contributor.authorNteziyaremye, Julius
dc.contributor.authorIramiot, Stanley Jacob
dc.contributor.authorNekaka, Rebecca
dc.contributor.authorMusaba, Milton W.
dc.contributor.authorWandabwa, Julius
dc.contributor.authorKisegerwa, Enoch
dc.contributor.authorKiondo, Paul
dc.date.accessioned2023-02-21T16:00:32Z
dc.date.available2023-02-21T16:00:32Z
dc.date.issued2020
dc.description.abstractAsymptomatic bacteriuria in pregnancy (ASBP) is associated with adverse pregnancy outcomes such as pyelonephritis, preterm or low birth weight delivery if untreated. The aim of this study was to determine the prevalence of asymptomatic bacteriuria, the isolated bacterial agents, and their antibiotic sensitivity patterns in pregnant women attending antenatal care at Mbale Hospital. Methods This was a cross sectional study in which 587 pregnant women with no symptoms and signs of urinary tract infection were recruited from January to March 2019. Mid-stream clean catch urine samples were collected from the women using sterile containers. The urine samples were cultured using standard laboratory methods. The bacterial colonies were identified and antibiotic sensitivity was done using disc diffusion method. Chi squared tests and logistic regression were done to identify factors associated with asymptomatic bacteriuria. A p value < 0.05 was considered statistically significant. Results Out of the 587 pregnant women, 22 (3.75%) tested positive for asymptomatic bacteriuria. Women aged 20–24 years were less likely to have ASBP when compared to women aged less than 20 years (AOR = 0.14, 95%CI 0.02–0.95, P = 0.004). The most common isolates in descending order were E. coli (n = 13, 46.4%) and S.aureus (n = 9, 32.1%). Among the gram negative isolates, the highest sensitivity was to gentamycin (82.4%) and imipenem (82.4%). The gram positive isolates were sensitive to gentamycin (90.9%) followed by imipenem (81.8%). All the isolates were resistant to sulphamethoxazole with trimethoprim (100%). Multidrug resistance was 82.4% among gram negative isolates and 72.4% among the gram positive isolates. Conclusion There was high resistance to the most commonly used antibiotics. There is need to do urine culture and sensitivity from women with ASBP so as to reduce the associated complications.en_US
dc.identifier.citationNteziyaremye J, Iramiot SJ, Nekaka R, Musaba MW, Wandabwa J, Kisegerwa E, et al. (2020) Asymptomatic bacteriuria among pregnant women attending antenatal care at Mbale Hospital, Eastern Uganda. PLoS ONE 15(3): e0230523. https://doi.org/10.1371/journal.pone.0230523en_US
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0230523
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7909
dc.language.isoenen_US
dc.publisherPloS oneen_US
dc.subjectAsymptomatic bacteriuriaen_US
dc.subjectPregnant womenen_US
dc.subjectAntenatal careen_US
dc.subjectMbale Hospitalen_US
dc.titleAsymptomatic bacteriuria among pregnant women attending antenatal care at Mbale Hospital, Eastern Ugandaen_US
dc.typeArticleen_US
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