Prevalence and Correlates of Mycoplasma genitalium Infection Among Female Sex Workers in Kampala, Uganda

Simple item page
dc.contributor.authorVandepitte, Judith
dc.contributor.authorMuller, Etienne
dc.contributor.authorBukenya, Justine
dc.contributor.authorNakubulwa, Susan
dc.contributor.authorKyakuwa, Nassim
dc.contributor.authorBuve, Anne
dc.contributor.authorWeiss, Helen
dc.contributor.authorHayes, Richard
dc.contributor.authorGrosskurth, Heiner
dc.date.accessioned2022-05-17T17:48:21Z
dc.date.available2022-05-17T17:48:21Z
dc.date.issued2012
dc.description.abstractThe importance of Mycoplasma genitalium in human immunodeficiency virus (HIV)–burdened sub–Saharan Africa is relatively unknown. We assessed the prevalence and explored determinants of this emerging sexually transmitted infection (STI) in high-risk women in Uganda. Methods. Endocervical swabs from 1025 female sex workers in Kampala were tested for Mycoplasma genitalium using a commercial Real-TM polymerase chain reaction assay. Factors associated with prevalent Mycoplasma genitalium, including sociodemographics, reproductive history, risk behavior, and HIV and other STIs, were examined using multivariable logistic regression. Results. The prevalence of Mycoplasma genitalium was 14% and higher in HIV-positive women than in HIVnegative women (adjusted odds ratio [OR], 1.64; 95% confidence interval [CI], 1.12–2.41). Mycoplasma genitalium infection was less prevalent in older women (adjusted OR, 0.61; 95% CI, .41–.90 for women ages 25–34 years vs ,25 years; adjusted OR, 0.32; 95% CI, .15–.71 for women $35 years vs those ,25 years) and in those who had been pregnant but never had a live birth (adjusted OR, 2.25; 95% CI, 1.04–4.88). Mycoplasma genitalium was associated with Neisseria gonorrhoeae (adjusted OR, 1.84; 95% CI, 1.13–2.98) and with Candida infection (adjusted OR, 0.41; 95% CI, .18–.91), and there was some evidence of association with Trichomonas vaginalis (adjusted OR, 1.56; 95% CI, 1.00–2.44). Conclusions. The relatively high prevalence of Mycoplasma genitalium and its association with prevalent HIV urgently calls for further research to explore the potential role this emerging STI plays in the acquisition and transmission of HIV infection.en_US
dc.identifier.citationVandepitte, J., Muller, E., Bukenya, J., Nakubulwa, S., Kyakuwa, N., Buvé, A., ... & Grosskurth, H. (2012). Prevalence and correlates of Mycoplasma genitalium infection among female sex workers in Kampala, Uganda. Journal of Infectious Diseases, 205(2), 289-296.en_US
dc.identifier.other10.1093/infdis/jir733
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/3248
dc.language.isoenen_US
dc.publisherJournal of Infectious Diseasesen_US
dc.subjectPrevalenceen_US
dc.subjectMycoplasma genitalium Infectionen_US
dc.subjectFemale Sex Workersen_US
dc.subjectUgandaen_US
dc.titlePrevalence and Correlates of Mycoplasma genitalium Infection Among Female Sex Workers in Kampala, Ugandaen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Prevalence and Correlates of Mycoplasma.pdf
Size:
221.25 KB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medical and Health Sciences