Recognition and reporting of suspected adverse drug reactions by surveyed healthcare professionals in Uganda: key determinants

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dc.contributor.authorKiguba, Ronald
dc.contributor.authorKaramagi, Charles
dc.contributor.authorWaako, Paul
dc.contributor.authorNdagije, Helen B.
dc.contributor.authorBird, Sheila M.
dc.date.accessioned2021-12-12T12:15:53Z
dc.date.available2021-12-12T12:15:53Z
dc.date.issued2014
dc.description.abstractTo assess extent and determinants of past month recognition of suspected adverse drug reactions (ADR) and past-year ADR reporting among healthcare professionals (HCPs) in Uganda. Setting: Geographically diverse health facilities (public, private for-profit, private not-for-profit). Participants: Of 2000 questionnaires distributed, 1345 were completed: return rate of 67%. Primary and secondary outcome measures: Per cent HCPs who suspected ADR in the past month; reported ADR in the past year. Results: Nurses were the majority (59%, 792/1345). Only half the respondents had heard about pharmacovigilance: 39% of nurses (295/763; 95% CI 35% to 42%), 70% otherwise (383/547; 95% CI 66% to 74%). One fifth (268/1289 or 21%; 95% CI 19% to 23%) had suspected an ADR in the previous 4 weeks, 111 of them were nurses; 15% (190/1296) had reported a suspected ADR in the past year, 103 of them were nurses. Past-month ADR suspicion was more likely by non-nurses (OR=1.7, 95% CI 1.16 to 2.40) and with medical research involvement (OR=1.5, 95% CI 1.05 to 2.15) but past-month receipt of patient ADR-complaint predominated (OR=19, 95% CI 14 to 28). Past-year ADR reporting was higher by hospital staff (OR=1.9, 95% CI 1.18 to 3.10), especially in medicine (OR=2.3, 95% CI 1.08 to 4.73); but lower from private for-profit health facilities (OR=0.5, 95% CI 0.28 to 0.77) and by older staff (OR=0.6, 95% CI 0.43 to 0.91); more likely by HCPs who had ever encountered a fatal ADR (OR=2.9, 95% CI 1.94 to 4.25), knew to whom to report (OR=1.7, 95% CI 1.18 to 2.46), or suggested how to improve ADR reporting (OR=1.6, 95% CI 1.04 to 2.49). Two attitudinal factors were important: diffidence and lethargy.en_US
dc.identifier.citationKiguba R, Karamagi C, Waako P, et al. Recognition and reporting of suspected adverse drug reactions by surveyed healthcare professionals in Uganda: key determinants. BMJ Open 2014;4:e005869. doi:10.1136/bmjopen-2014- 005869.doi:10.1136/bmjopen-2014- 005869en_US
dc.identifier.other10.1136/bmjopen-2014- 005869
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/345
dc.language.isoenen_US
dc.publisherBMJ Openen_US
dc.subjectadverse drugen_US
dc.subjecthealthcare professionalsen_US
dc.subjectUgandaen_US
dc.titleRecognition and reporting of suspected adverse drug reactions by surveyed healthcare professionals in Uganda: key determinantsen_US
dc.typeArticleen_US
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