PIERS Proteinuria: Relationship With Adverse Maternal and Perinatal Outcome

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dc.contributor.authorPayne, Beth
dc.contributor.authorMagee, Laura A.
dc.contributor.authorCôté, Anne-Marie
dc.contributor.authorHutcheon, Jennifer A.
dc.contributor.authorLi, Jing
dc.contributor.authorKyle, Phillipa M.
dc.contributor.authorMenzies, Jennifer M.
dc.contributor.authorMoore, Peter
dc.contributor.authorParker, Claire
dc.contributor.authorPullar, Barbra
dc.contributor.authorDadelszen, Peter von
dc.contributor.authorWalters, Barry N.
dc.date.accessioned2022-01-21T22:03:50Z
dc.date.available2022-01-21T22:03:50Z
dc.date.issued2011
dc.description.abstractTo examine the ability of three different proteinuria assessment methods (urinary dipstick, spot urine protein:creatinine ratio [Pr/Cr], and 24-hour urine collection) to predict adverse pregnancy outcomes Methods: We performed a prospective multicentre cohort study, PIERS (Preeclampsia Integrated Estimate of RiSk), in seven academic tertiary maternity centres practising expectant management of preeclampsia remote from term in Canada, New Zealand, and Australia- Eligible women were those admitted with preeclampsia who had at least one antenatal proteinuria assessment by urinary dipstick, spot urine Pr/Cr ratio, and/or 24-hour urine collection Proteinuria assessment was done either visually at the bedside (by dipstick) or by hospital clinical laboratories for spot urine Pr/Cr and 24-hour urine collection- We calculated receiver operating characteristic area under the curve (95% CI) for each proteinuria method and each of the combined adverse maternal outcomes (within 48 hours) or adverse perinatal outcomes (at any time) Models with AUC ≥ 0-70 were considered of interest- Analyses were run for all women who had each type of proteinuria assessment and for a cohort of women (“ALL measures”) who had all three proteinuria assessmentsen_US
dc.identifier.citationPayne, B., Magee, L. A., Côté, A. M., Hutcheon, J. A., Li, J., Kyle, P. M., ... & PIERS Study Group. (2011). PIERS proteinuria: relationship with adverse maternal and perinatal outcome. Journal of Obstetrics and Gynaecology Canada, 33(6), 588-597.en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1701216316349076
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1413
dc.language.isoenen_US
dc.publisherJournal of Obstetrics and Gynaecologyen_US
dc.subjectProteinuriaen_US
dc.subjectPreeclampsiaen_US
dc.subjectReceiver operating characteristic curveen_US
dc.subjectdiagnostic accuracyen_US
dc.subjectCompeting Interestsen_US
dc.titlePIERS Proteinuria: Relationship With Adverse Maternal and Perinatal Outcomeen_US
dc.typeArticleen_US
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