Users May Lack Confidence in ART for HIV Prevention: A Qualitative Analysis
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Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
Conference on retroviruses and opportunistic infections (CROI)
Abstract
Antiretroviral-based approaches to HIV prevention have
been shown to reduce new infections in clinical trials and
demonstration settings.
To optimize uptake and anticipate barriers to effective
rollout, we must understand users’ perspectives on
antiretroviral treatment (ART) for prevention of HIV
transmission.
We explored serodiscordant couples’ understandings of
and feelings about treatment as prevention using
qualitative data from the Partners Demonstration Project. The Partners Demonstration Project employed an
integrated delivery strategy of daily oral pre-exposure
prophylaxis (PrEP) and ART for serodiscordant couples
in Kenya and Uganda.
PrEP use was time-limited and discontinued after HIVinfected
partners had been on ART for 6 months.
Multiple in-depth qualitative interviews were conducted
with a subset of 48 couples from the Kampala, Uganda
Partners Demonstration Project site (N interviews=195).
Interview topics included: (a) perceived purpose and
meanings of PrEP and ART; (b) adherence; (c)
experiences of PrEP discontinuation; and (d)
understandings of antiretroviral treatment as prevention.
Interviews were audio-recorded, transcribed into English
and coded using Atlas.ti software by two trained analysts.
Coded data were inductively analyzed to identify themes
representing couples’ understandings of and feelings
about using ART for prevention of HIV transmission.
Categories were developed to represent the themes.
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Citation
Wyatt, M. A., Pisarski, E. E., Baeten, J., Heffron, R., Nakku-Joloba, E., Muwonge, T. R., ... & Ware, N. C. (2017). Users may lack confidence in ART for HIV prevention: a qualitative analysis. In Conference on retroviruses and opportunistic infections (CROI).