Cardiovascular risk factors and clinical outcomes of patients hospitalized with COVID-19 pneumonia in Somalia

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dc.contributor.authorAhmed, Mohammed A.M.
dc.contributor.authorMohamud Hussein, Ahmed
dc.contributor.authorAhmed Moalim Abdullahi, Aweis
dc.contributor.authorYusuf Ahmed, Abdirizak
dc.contributor.authorHussain, Hamdi M.A.
dc.contributor.authorMohamed Ali, Abdiaziz
dc.contributor.authorAbdinur Barre, Abdulqadir
dc.contributor.authorMohamud Yusuf, Farhia
dc.contributor.authorOlum, Ronald
dc.contributor.authorGoitom Sereke, Senai
dc.contributor.authorAhmed Elfadul, Maisa
dc.contributor.authorColebunders, Robert
dc.contributor.authorBongomin, Felix
dc.date.accessioned2023-01-22T12:13:20Z
dc.date.available2023-01-22T12:13:20Z
dc.date.issued2022
dc.description.abstractCoronavirus disease-2019 (COVID-19) is a potentially life-threatening illness with no established treatment. Cardiovascular risk factors (CRFs) exacerbate COVID-19 morbidity and mortality. Objective: To determine the prevalence of CRF and clinical outcomes of patients hospitalized with COVID-19 in a tertiary hospital in Somalia. Methods: We reviewed the medical records of patients aged 18 years or older with a real-time polymerase chain reaction (RT-PCR)–confirmed COVID-19 hospitalized at the De Martino Hospital in Mogadishu, Somalia, between March and July 2020. Results: We enrolled 230 participants; 159 (69.1%) males, median age was 56 (41–66) years. In-hospital mortality was 19.6% (n = 45); 77.8% in the intensive care unit (ICU) compared with 22.2%, in the general wards (p < 0.001). Age ⩾ 40 years [odds ratio (OR): 3.6, 95% confidence interval (CI): 1.2–10.6, p = 0.020], chronic heart disease (OR: 9.3, 95% CI: 2.2–38.9, p = 0.002), and diabetes mellitus (OR: 3.2, 95% CI: 1.6–6.2, p < 0.001) were associated with increased odds of mortality. Forty-three (18.7%) participants required ICU admission. Age ⩾ 40 years (OR: 7.5, 95% CI: 1.7–32.1, p = 0.007), diabetes mellitus (OR: 3.2, 95% CI: 1.6–6.3, p < 0.001), and hypertension (OR: 2.5, 95% CI: 1.2–5.2, p = 0.014) were associated with ICU admission. For every additional CRF, the odds of admission into the ICU increased threefold (OR: 2.7, 95% CI: 1.2–5.2, p < 0.001), while the odds of dying increased twofold (OR: 2.1, 95% CI: 1.3–3.2, p < 0.001). Conclusions: We report a very high prevalence of CRF among patients hospitalized with COVID-19 in Somalia. Mortality rates were unacceptably high, particularly among those with advanced age, underlying chronic heart disease, and diabetes.en_US
dc.identifier.citationAhmed, M. A., Hussein, A. M., Abdullahi, A. A. M., Ahmed, A. Y., Hussain, H. M., Ali, A. M., ... & Bongomin, F. (2022). Cardiovascular risk factors and clinical outcomes of patients hospitalized with COVID-19 pneumonia in Somalia. Therapeutic Advances in Infectious Disease, 9, 20499361221095731. DOI: 10.1177/ 20499361221095731en_US
dc.identifier.other10.1177/ 20499361221095731
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7100
dc.language.isoenen_US
dc.publisherTherapeutic Advances in Infectious Diseaseen_US
dc.subjectCardiovascular diseaseen_US
dc.subjectClinical outcomesen_US
dc.subjectCOVID-19en_US
dc.subjectDiabetesen_US
dc.subjectMortalityen_US
dc.subjectRisk factorsen_US
dc.titleCardiovascular risk factors and clinical outcomes of patients hospitalized with COVID-19 pneumonia in Somaliaen_US
dc.typeArticleen_US
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