Mycobacterium tuberculosis Microbiologic and Clinical Treatment Outcomes in a Randomized Trial of Immediate versus CD4+ -Initiated Antiretroviral Therapy in HIV-Infected Adults with a High CD4+ Cell Count

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dc.contributor.authorChamie, Gabriel
dc.contributor.authorCharlebois, Edwin D.
dc.contributor.authorWalusimbi-Nanteza, Maria
dc.contributor.authorMugerwa, Roy D.
dc.contributor.authorMayanja, Harriet
dc.contributor.authorOkwera, Alphonse
dc.contributor.authorWhalen, Christopher C.
dc.contributor.authorHavlir, Diane V.
dc.date.accessioned2023-03-06T15:03:38Z
dc.date.available2023-03-06T15:03:38Z
dc.date.issued2010
dc.description.abstractIn a prospective randomized, controlled trial in Uganda comparing the efficacy of antiretroviral therapy during tuberculosis therapy with the efficacy of tuberculosis therapy alone in HIV-infected patients with tuberculosis who have a CD4+ cell count >350 cells/µL, it was found that antiretroviral therapy did not accelerate microbiologic, radiographic, or clinical responses to tuberculosis therapy: 18% of participants had sputum smears positive for Mycobacterium tuberculosis after 5 months of tuberculosis therapy, despite having had negative culture results.en_US
dc.identifier.citationChamie, G., Charlebois, E. D., Srikantiah, P., Walusimbi-Nanteza, M., Mugerwa, R. D., Mayanja, H., ... & Havlir, D. V. (2010). Mycobacterium tuberculosis microbiologic and clinical treatment outcomes in a randomized trial of immediate versus CD4+-initiated antiretroviral therapy in HIV-infected adults with a high CD4+ cell count. Clinical infectious diseases, 51(3), 359-362.https://doi.org/10.1086/654799en_US
dc.identifier.issn1537-6591
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8082
dc.language.isoenen_US
dc.publisherClinical infectious diseasesen_US
dc.subjectMycobacterium tuberculosis Microbiologicen_US
dc.subjectHigh CD4+ Cell Counten_US
dc.subjectHIV-Infected Adultsen_US
dc.subjectClinical Treatment Outcomesen_US
dc.titleMycobacterium tuberculosis Microbiologic and Clinical Treatment Outcomes in a Randomized Trial of Immediate versus CD4+ -Initiated Antiretroviral Therapy in HIV-Infected Adults with a High CD4+ Cell Counten_US
dc.typeTechnical Reporten_US
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