Modelling the Use of Insecticide-Treated Cattle to Control Tsetse and Trypanosoma brucei rhodesiense in a Multi-host Population
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Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Bulletin of Mathematical biology
Abstract
We present a mathematical model for the transmission of Trypanosoma brucei rhodesiense by tsetse vectors to a multi-host population. To control tsetse and T. b. rhodesiense, a proportion, ψ, of cattle (one of the hosts considered in the model)
is taken to be kept on treatment with insecticides. Analytical expressions are obtained for the basic reproduction number, R0n in the absence, and RT 0n in the presence of insecticide-treated cattle (ITC). Stability analysis of the disease-free equilibrium was
carried out for the case when there is one vertebrate host untreated with insecticide. By considering three vertebrate hosts (cattle, humans and wildlife) the sensitivity analysis was carried out on the basic reproduction number (RT 03) in the absence and presence of ITC. The results show that RT 03 is more sensitive to changes in the tsetse mortality. The model is then used to study the control of tsetse and T. b. rhodesiense in humans through application insecticides to cattle either over the whole-body or to restricted areas of the body known to be favoured tsetse feeding sites. Numerical results show that while both ITC strategies result in decreases in tsetse density and in the incidence of T. b. rhodesiense in humans, the restricted application technique results
Description
Keywords
Trypanosomiasis, Tsetse, Vector control, Insecticide-treated cattle
Citation
Kajunguri, D., Hargrove, J. W., Ouifki, R., Mugisha, J. Y. T., Coleman, P. G., & Welburn, S. C. (2014). Modelling the use of insecticide-treated cattle to control tsetse and Trypanosoma brucei rhodesiense in a multi-host population. Bulletin of Mathematical biology, 76(3), 673-696. DOI 10.1007/s11538-014-9938-6