The Joint Mobile Emerging Disease Clinical Capability (JMEDICC) laboratory approach: Capabilities for high-consequence pathogen clinical research

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dc.contributor.authorNaluyima, Prossy
dc.contributor.authorKayondo, Willy
dc.contributor.authorWandege, Joseph
dc.contributor.authorKagabane, Sharon
dc.contributor.authorTumubeere, Lydia
dc.contributor.authorKusiima, Brenda
dc.contributor.authorKibombo, Daniel
dc.contributor.authorAtukunda, Sharon
dc.contributor.authorNanteza, Christine
dc.contributor.authorZaman, Saima
dc.date.accessioned2023-02-22T19:35:09Z
dc.date.available2023-02-22T19:35:09Z
dc.date.issued2019
dc.description.abstractFollowing the 2013–2016 Ebola virus outbreak in West Africa, numerous groups advocated for the importance of executing clinical trials in outbreak settings. The difficulties associated with obtaining reliable data to support regulatory approval of investigational vaccines and therapeutics during that outbreak were a disappointment on a research and product development level, as well as on a humanitarian level. In response to lessons learned from the outbreak, the United States Department of Defense established a multi-institute project called the Joint Mobile Emerging Disease Intervention Clinical Capability (JMEDICC). JMEDICC’s primary objective is to establish the technical capability in western Uganda to execute clinical trials during outbreaks of high-consequence pathogens such as the Ebola virus. A critical component of clinical trial execution is the establishment of laboratory operations. Technical, logistical, and political challenges complicate laboratory operations, and these challenges have been mitigated by JMEDICC to enable readiness for laboratory outbreak response operations.en_US
dc.identifier.citationNaluyima, P., Kayondo, W., Ritchie, C., Wandege, J., Kagabane, S., Tumubeere, L., ... & Martins, K. A. (2019). The Joint Mobile Emerging Disease Clinical Capability (JMEDICC) laboratory approach: capabilities for high-consequence pathogen clinical research. PLoS Neglected Tropical Diseases, 13(12), e0007787.https://doi.org/10.1371/journal.pntd.0007787en_US
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7938
dc.language.isoenen_US
dc.publisherPLoS Neglected Tropical Diseasesen_US
dc.subjectpathogenen_US
dc.subjectJoint Mobile Emerging Disease Clinical Capabilityen_US
dc.titleThe Joint Mobile Emerging Disease Clinical Capability (JMEDICC) laboratory approach: Capabilities for high-consequence pathogen clinical researchen_US
dc.typeArticleen_US
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