Sero-Prevalence and Factors Associated with Helicobacter pylori Infection in a Rural Population in Eastern Uganda: A Community Cross-sectional Study

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dc.contributor.authorNekaka, Rebecca
dc.contributor.authorOboth, Paul
dc.contributor.authorNteziyaremye, Julius
dc.contributor.authorGavamukulya, Yahaya
dc.contributor.authorSsenyonga, Lydia V. N.
dc.contributor.authorIramiot, Jacob Stanley
dc.date.accessioned2023-01-30T19:30:46Z
dc.date.available2023-01-30T19:30:46Z
dc.date.issued2021
dc.description.abstractGlobally, 50% or more of the world’s population is infected with Helicobacter pylori making it the most widely spread bacteria across the world. The low developed countries are more overburdened by Helicobacter pylori infection than the developed countries. H. pylori infection is associated with duodenal ulcer, chronic atrophic gastritis (CAG), lymphomas, and adenocarcinoma. This study reports the prevalence of H. pylori and its associated factors in Eastern Uganda. Materials and methods: A cross-sectional study involving 275 participants was carried out in eastern Uganda. H. pylori serology was done and face to face interviewer-administered questionnaire were used for data collection. Data were entered in Microsoft Excel and imported to Stata version 14 for analysis and a P value of <0.05 was considered statistically significant. Results: The seroprevalence of H. pylori was 27.3% (75/275) with 28.4% (50/176) of the females being positive compared to 25.3% (25/99) of the males. Consumption of animal products (meat, milk, and eggs) was the only statistically significant factor associated with H. pylori seropositivity (P <0.001, 95% CI =1.934-4.209, AOR=2.85). Conclusion: The H. pylori seroprevalence is high in eastern Uganda. Consumption of animal products was a positive predictor of infectivity.en_US
dc.identifier.citationNekaka, R., Oboth, P., Nteziyaremye, J., Gavamukulya, Y., Ssenyonga, L. V., & Iramiot, J. S. (2021). Sero prevalence and factors associated with Helicobacter pylori infection in a rural population in Eastern Uganda a community cross sectional study. Primary Health Care: Open Access, 11(4), 1-9.en_US
dc.identifier.urihttps://www.iomcworld.org/open-access/sero-prevalence-and-factors-associated-with-helicobacter-pylori-infection-in-a-rural-population-in-eastern-uganda-a-community-cros-70767.html
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7411
dc.language.isoenen_US
dc.publisherPrimary Health Care: Open Accessen_US
dc.subjectHelicobacter pylorien_US
dc.subjectAnimal productsen_US
dc.subjectSeroprevalenceen_US
dc.titleSero-Prevalence and Factors Associated with Helicobacter pylori Infection in a Rural Population in Eastern Uganda: A Community Cross-sectional Studyen_US
dc.typeArticleen_US
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