Sero-Prevalence and Factors Associated with Helicobacter pylori Infection in a Rural Population in Eastern Uganda: A Community Cross-sectional Study
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Primary Health Care: Open Access
Abstract
Globally, 50% or more of the world’s population is infected with
Helicobacter pylori making it the most widely spread bacteria across the
world. The low developed countries are more overburdened by Helicobacter
pylori infection than the developed countries. H. pylori infection is associated
with duodenal ulcer, chronic atrophic gastritis (CAG), lymphomas, and
adenocarcinoma. This study reports the prevalence of H. pylori and its
associated factors in Eastern Uganda.
Materials and methods: A cross-sectional study involving 275 participants
was carried out in eastern Uganda. H. pylori serology was done and face to
face interviewer-administered questionnaire were used for data collection.
Data were entered in Microsoft Excel and imported to Stata version 14 for
analysis and a P value of <0.05 was considered statistically significant.
Results: The seroprevalence of H. pylori was 27.3% (75/275) with 28.4%
(50/176) of the females being positive compared to 25.3% (25/99) of the
males. Consumption of animal products (meat, milk, and eggs) was the only
statistically significant factor associated with H. pylori seropositivity (P
<0.001, 95% CI =1.934-4.209, AOR=2.85).
Conclusion: The H. pylori seroprevalence is high in eastern Uganda.
Consumption of animal products was a positive predictor of infectivity.
Description
Keywords
Helicobacter pylori, Animal products, Seroprevalence
Citation
Nekaka, R., Oboth, P., Nteziyaremye, J., Gavamukulya, Y., Ssenyonga, L. V., & Iramiot, J. S. (2021). Sero prevalence and factors associated with Helicobacter pylori infection in a rural population in Eastern Uganda a community cross sectional study. Primary Health Care: Open Access, 11(4), 1-9.