Assessing the impact of HIV support groups on antiretroviral therapy adherence and viral suppression in the African cohort study

dc.contributor.authorMbah, Prudence
dc.contributor.authorIroezindu, Michael
dc.contributor.authorEsber, Allahna L.
dc.contributor.authorDear, Nicole
dc.contributor.authorReed, Domonique
dc.contributor.authorAdamu, Yakubu
dc.contributor.authorKibuuka, Hannah
dc.contributor.authorMaswai, Jonah
dc.contributor.authorBahemana, Emmanuel
dc.contributor.authorAke, Julie A.
dc.contributor.authorPolyak, Christina S.
dc.date.accessioned2022-12-06T11:07:45Z
dc.date.available2022-12-06T11:07:45Z
dc.date.issued2021
dc.description.abstractSupport groups for people living with HIV (PLWH) may improve HIV care adherence and outcomes. We assessed the impact of support group attendance on antiretroviral therapy (ART) adherence and viral suppression in four African countries. Methods: The ongoing African Cohort Study (AFRICOS) enrolls participants at 12 clinics in Kenya, Uganda, Tanzania, and Nigeria. Self-reported attendance of any support group meetings, self-reported ART adherence, and HIV RNA are assessed every 6 months. Logistic regression models with generalized estimating equations were used to estimate adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) for support group attendance and other factors potentially associated with ART adherence and viral suppression. Results: From January 2013 to December 1, 2019, 1959 ART-experienced PLWH were enrolled and 320 (16.3%) reported any support group attendance prior to enrollment. Complete ART adherence, with no missed doses in the last 30 days, was reported by 87.8% while 92.4% had viral suppression <1000copies/mL across all available visits. There was no association between support group attendance and ART adherence in unadjusted (OR 1.01, 95% CI 0.99–1.03) or adjusted analyses (aOR 1.00, 95% CI 0.98–1.02). Compared to PLWH who did not report support group attendance, those who did had similar odds of viral suppression in unadjusted (OR 0.99, 95% CI 0.978–1.01) and adjusted analyses (aOR 0.99, 95% CI 0.97–1.01). Conclusion: Support group attendance was not associated with significantly improved ART adherence or viral suppression, although low support group uptake may have limited our ability to detect a statistically significant impact.en_US
dc.identifier.citationMbah, P., Iroezindu, M., Esber, A. L., Dear, N., Reed, D., Adamu, Y., ... & Crowell, T. A. (2021). Assessing the impact of HIV support groups on antiretroviral therapy adherence and viral suppression in the African cohort study. BMC Infectious Diseases, 21(1), 1-12. https://doi.org/10.1186/s12879-021-06390-3en_US
dc.identifier.urihttps://doi.org/10.1186/s12879-021-06390-3
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/5970
dc.language.isoenen_US
dc.publisherBMC Infectious Diseasesen_US
dc.subjectAfricaen_US
dc.subjectART adherenceen_US
dc.subjectHIVen_US
dc.subjectSupport groupen_US
dc.subjectViral suppressionen_US
dc.titleAssessing the impact of HIV support groups on antiretroviral therapy adherence and viral suppression in the African cohort studyen_US
dc.typeArticleen_US
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