Assessing the impact of HIV support groups on antiretroviral therapy adherence and viral suppression in the African cohort study
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
BMC Infectious Diseases
Abstract
Support groups for people living with HIV (PLWH) may improve HIV care adherence and outcomes.
We assessed the impact of support group attendance on antiretroviral therapy (ART) adherence and viral
suppression in four African countries.
Methods: The ongoing African Cohort Study (AFRICOS) enrolls participants at 12 clinics in Kenya, Uganda, Tanzania,
and Nigeria. Self-reported attendance of any support group meetings, self-reported ART adherence, and HIV RNA
are assessed every 6 months. Logistic regression models with generalized estimating equations were used to
estimate adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) for support group attendance and
other factors potentially associated with ART adherence and viral suppression.
Results: From January 2013 to December 1, 2019, 1959 ART-experienced PLWH were enrolled and 320 (16.3%)
reported any support group attendance prior to enrollment. Complete ART adherence, with no missed doses in the
last 30 days, was reported by 87.8% while 92.4% had viral suppression <1000copies/mL across all available visits.
There was no association between support group attendance and ART adherence in unadjusted (OR 1.01, 95% CI
0.99–1.03) or adjusted analyses (aOR 1.00, 95% CI 0.98–1.02). Compared to PLWH who did not report support group
attendance, those who did had similar odds of viral suppression in unadjusted (OR 0.99, 95% CI 0.978–1.01) and
adjusted analyses (aOR 0.99, 95% CI 0.97–1.01).
Conclusion: Support group attendance was not associated with significantly improved ART adherence or viral
suppression, although low support group uptake may have limited our ability to detect a statistically significant impact.
Description
Keywords
Africa, ART adherence, HIV, Support group, Viral suppression
Citation
Mbah, P., Iroezindu, M., Esber, A. L., Dear, N., Reed, D., Adamu, Y., ... & Crowell, T. A. (2021). Assessing the impact of HIV support groups on antiretroviral therapy adherence and viral suppression in the African cohort study. BMC Infectious Diseases, 21(1), 1-12. https://doi.org/10.1186/s12879-021-06390-3