The Global Epidemiology of Viral-induced Acute Liver Failure: a systematic review protocol

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dc.contributor.authorPatterson, Jenna
dc.contributor.authorHussey, Hannah Sophia
dc.contributor.authorSetshedi, Mashiko
dc.contributor.authorKagina, Benjamin
dc.contributor.authorMuloiwa, Rudzani
dc.date.accessioned2023-02-14T18:33:44Z
dc.date.available2023-02-14T18:33:44Z
dc.date.issued2019
dc.description.abstractThe burden of viral-induced acute liver failure (ALF) around the world still remains unclear, with little to no data collected regarding the disease incidence in general and synthesised data on the relative contribution of different viruses to the aetiology of ALF is missing in the field. The aim of this review is to estimate the burden (prevalence, incidence, mortality, hospitalisation) of ALF following infection HAV, HBV, HCV, HDV, HEV, EBV), HSV1, HSV2, VZV, parvo-virus B19, HPIVs, YFV, HVV-6, CMV, CA16 and/or HAdVs. Establishing the common aetiologies of viral-induced ALF, which vary geographically, is important so that: (1) treatment can be initiated quickly, (2) contraindications to liver transplant can be identified, (3) prognoses can be deterined more accurately, and most importantly, (4) vaccination against viral ALF aetiologies can be prioritised especially in under-resourced regions with public health risks associated with the relevant attributable diseases.en_US
dc.identifier.citationPatterson, J., Hussey, H. S., Abdullahi, L. H., Silal, S., Goddard, L., Setshedi, M., ... & Muloiwa, R. (2019). The global epidemiology of viral-induced acute liver failure: a systematic review protocol. BMJ open, 9(8), e029819.http://dx.doi.org/10.1136/bmjopen-2019-029819en_US
dc.identifier.issn2044-6055
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/7793
dc.language.isoenen_US
dc.publisherBMJ openen_US
dc.subjectacute liver failureen_US
dc.subjectincidenceen_US
dc.subjectaetiologiesen_US
dc.titleThe Global Epidemiology of Viral-induced Acute Liver Failure: a systematic review protocolen_US
dc.typeArticleen_US
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