Hepatitis B incidence and prevention with antiretroviral therapy among HIV positive individuals in Rakai, Uganda
dc.contributor.author | Seremba, E. | |
dc.contributor.author | Ssempijja, V. | |
dc.contributor.author | Kalibbala, S. | |
dc.contributor.author | Gray, R. H. | |
dc.contributor.author | Wawer, M. J. | |
dc.contributor.author | Nalugoda, F. | |
dc.contributor.author | Casper, C. | |
dc.contributor.author | Phipps, W. | |
dc.contributor.author | Ocama, P. | |
dc.contributor.author | Serwadda, D. | |
dc.contributor.author | Thomas, D. L. | |
dc.contributor.author | Reynolds, S. J. | |
dc.date.accessioned | 2022-01-20T21:25:19Z | |
dc.date.available | 2022-01-20T21:25:19Z | |
dc.date.issued | 2017 | |
dc.description.abstract | Antiretroviral therapy (ART) may interfere with replication of hepatitis B (HBV) raising the hypothesis that HBV infection might be prevented by ART. We investigated the incidence and risk factors associated with HBV among HIV-infected adults in Rakai, Uganda. Methods—We screened stored sera from 944 HIV-infected adults enrolled in the Rakai Community Cohort Study between September 2003 and March 2015 for evidence of HBV exposure. Serum from participants who tested anti-HBc negative (497) at baseline were tested over 3-7 consecutive survey rounds for incident HBV. Poisson incidence methods were used to estimate incidence of HBV with 95% confidence intervals while Cox proportional regression methods were used to estimate hazard ratios. | en_US |
dc.identifier.citation | Seremba, E., Ssempijja, V., Kalibbala, S., Gray, R. H., Wawer, M. J., Nalugoda, F., ... & Reynolds, S. J. (2017). Hepatitis B incidence and prevention with antiretroviral therapy among HIV positive individuals in Rakai, Uganda. AIDS (London, England), 31(6), 781. doi:10.1097/QAD.0000000000001399. | en_US |
dc.identifier.other | 10.1097/QAD.0000000000001399. | |
dc.identifier.uri | https://nru.uncst.go.ug/xmlui/handle/123456789/1365 | |
dc.language.iso | en | en_US |
dc.publisher | AIDS (London, England) | en_US |
dc.subject | Hepatitis B | en_US |
dc.subject | Antiretroviral therapy | en_US |
dc.subject | HIV positive individuals | en_US |
dc.subject | Rakai | en_US |
dc.subject | Uganda | en_US |
dc.title | Hepatitis B incidence and prevention with antiretroviral therapy among HIV positive individuals in Rakai, Uganda | en_US |
dc.type | Article | en_US |
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