Molecular characterization of SAT 2 foot-and-mouth disease virus from post-outbreak slaughtered animals: implications for disease control in Uganda
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Date
2010
Journal Title
Journal ISSN
Volume Title
Publisher
Epidemiology & Infection
Abstract
In Uganda, limiting the extent of foot-and-mouth disease (FMD) spread during outbreaks
involves short-term measures such as ring vaccination and restrictions of the movement of
livestock and their products to and from the affected areas. In this study, the presence of FMD
virus RNA was investigated in cattle samples 3 months after FMD quarantine measures had been
lifted following an outbreak in 2004. Oropharyngeal tissue samples were obtained from 12 cattle
slaughtered in a small town abattoir in Kiboga. FMD virus RNA was detected by diagnostic
RT–PCR in nine of the 12 tissue samples. Part of the coding region for the capsid protein VP1
was amplified and sequenced. All samples were identified as belonging to the SAT 2 serotype.
The implications for FMD control of both virus introduction into Uganda and the presence of
carrier animals following outbreaks are discussed.
Description
Keywords
FMD control, SAT 2, sequence divergence
Citation
Balinda, S. N., Belsham, G. J., Masembe, C., Sangula, A. K., Siegismund, H. R., & Muwanika, V. B. (2010). Molecular characterization of SAT 2 foot-and-mouth disease virus from post-outbreak slaughtered animals: implications for disease control in Uganda. Epidemiology & Infection, 138(8), 1204-1210.doi:10.1017/S0950268809991427