Analgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract
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Date
2017
Authors
Rwai Waweru, Wilson
Obado Osuwat, Lawrence
Wambui Mureithi, Connie
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Abstract
The present study sought to evaluate the anti-inflammatory and analgesic activities of ethanolic extract from Tradescantia fluminensis leaves. Methods: The crude leaf extract of T. fluminensis was investigated for anti-inflammatory and analgesic activities in Wistar Albino rats and mice respectively. The anti-inflammatory activity was investigated using egg albumin induced oedema model while acetic acid and formalin-induced paw licking models were used to evaluate the analgesic activity. Results: The extract showed a significant (P<0.05) dose-dependent inhibition of inflammation and pain compared to the control group. Conclusion: The leaf extract possesses anti-inflammatory and analgesic activities. The activities could be attributed to phytochemicals present in the plant.
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Keywords
Tradescantia fluminensis, Analgesic activity, Anti-inflammatory activity
Citation
Waweru, W. R., Osuwat, L. O., & Mureithi, C. W. (2017). Analgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract. The Journal of Phytopharmacology