Asymptomatic Bacteriuria and Candida Colonization among Pregnant Women in a District Hospital in Eastern Uganda
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Journal of Advances in Medicine and Medical Research
Abstract
Urinary tract infection (UTI) is the most common reason for which antimicrobials are
prescribed in pregnancy Worldwide. This study aimed to determine the prevalence of
asymptomatic bacteriuria, Candida colonization and antimicrobial susceptibility patterns among
pregnant women attending antenatal in a District Hospital in Eastern Uganda.
Materials and Methods: A descriptive cross sectional study was conducted in which pregnant
mothers who had come for routine antenatal care were counseled and their consents obtained before taking off urine samples for laboratory diagnosis. For those samples found to have pus cells,
culture and sensitivity test was done to identify the organisms and determine susceptibility to
particular antibiotics and antifungal agents.
Results: Gram negative isolates were more sensitive to meropenem (100%), and ciprofloxacin
(93.8%) but less sensitive to trimethoprim/sulphurmethoxazole (20%), Ceftazidime (7%), and
Cefepime (6%). Gram positive isolates were more sensitive to vancomycin (100%), meropenem
(87%) and linezolid (88.1%) but less sensitive to Cefotaxime (31%) and Trimethoprim /
sulphurmethoxazole (14%). All bacteria isolated in this study were multi-drug resistant (MDR). All
Candida isolates were susceptible to Econazole and Nystatin whereas all isolates were resistant to
Griseofulvin.
Conclusion: The prevalence of asymptomatic bacteriuria among pregnant women in Butaleja
district is high with many of the bacteria isolated exhibiting resistance to the commonly used
antibiotics. Antifungal resistance was common in this study.
Description
Keywords
Asymptomatic bacteriuria, Antimicrobial resistance, UTI, Pregnant women
Citation
Fredrick, B., Shadrack, M., Prossy, N., Ismail, O., Sam, I., Mirembe, N. M., ... & Stanley, I. J. (2019). Asymptomatic Bacteriuria and Candida Colonization among Pregnant Women in a District Hospital in Eastern Uganda. J Adv Med Med Res, 29(10), 1-10. DOI: 10.9734/JAMMR/2019/v29i1030130