High Frequency of False-Positive Hepatitis C Virus Enzyme-Linked Immunosorbent Assay in Rakai, Uganda
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Date
2013
Journal Title
Journal ISSN
Volume Title
Publisher
Clinical infectious diseases
Abstract
The prevalence of hepatitis C virus (HCV) infection in sub-
Saharan Africa remains unclear. We tested 1000 individuals
from Rakai, Uganda, with the Ortho version 3.0 HCV
enzyme-linked immunosorbent assay. All serologically positive
samples were tested for HCV RNA. Seventy-six of the
1000 (7.6%) participants were HCV antibody positive; none
were confirmed by detection of HCV RNA.
Description
Keywords
Hepatitis C virus, ELISA, Africa
Citation
Mullis, C. E., Laeyendecker, O., Reynolds, S. J., Ocama, P., Quinn, J., Boaz, I., ... & Stabinski, L. (2013). High frequency of false-positive hepatitis C virus enzyme-linked immunosorbent assay in Rakai, Uganda. Clinical infectious diseases, 57(12), 1747-1750. DOI: 10.1093/cid/cit602