Browsing by Author "Sebunya, Robert"

Now showing 1 - 5 of 5
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    Brain magnetic resonance imaging fndings among children with epilepsy in two urban hospital settings, Kampala-Uganda: a descriptive study
    (BMC Medical Imaging, 2022) Apolot, Denise; Erem, Geofrey; Nassanga, Rita; Kiggundu, Daniel; Tumusiime, Crescent Max; Teu, Anneth; Mugisha, Alex Mwesigwa; Sebunya, Robert
    Epilepsy is one of the most common neurological conditions in children worldwide. Its presentation is heterogeneous, with diverse underlying aetiology, clinical presentation, and prognosis. Structural brain abnormalities are among the recognized causes of epilepsy. Brain Magnetic Resonance Imaging (MRI) is the imaging modality of choice for epilepsy workup. We aimed to determine the prevalence and describe the structural abnormalities identified in the brain MRI studies performed on children with epilepsy from two urban hospitals in Kampala, Uganda.
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    Impact of Secondary and Tertiary Neonatal Interventions on Neonatal Mortality in a Low- Resource Limited Setting Hospital in Uganda: A Retrospective Study
    (BMJ open, 2022) Kirabira, Victoria Nakibuuka; Nakaggwa, Florence; Nazziwa, Ritah; Nalunga, Sanyu; Nasiima, Ritah; Nyagabyaki, Catherine; Sebunya, Robert; Latigi, Grace; Pirio, Patricia; Ahmadzai, Malalay; Ojom, Lawrence; Nabwami, Immaculate; Burgoine, Kathy; Blencowe, Hannah
    To assess the impact of secondary and tertiary level neonatal interventions on neonatal mortality over a period of 11 years.During the study period, a total of 25 316 neonates were admitted, of which 1853 (7.3%) died. The average inpatient mortality reduced from 8.2% during phase I to 5.7% during phase II (p=0.001). The CFR for prematurity reduced from 16.2% to 9.2% (p=0.001). There was a trend in reduction for the CFR of perinatal asphyxia from 14.9% to 13.0% (p=0.34). The CFR for sepsis had a more than a twofold increase (3%–6.8% p=0.001) between phase I and phase II. Implementation of secondary and tertiary neonatal care in resource-limited settings is feasible. This study shows that these interventions can significantly reduce the neonatal mortality, with the largest impact seen in the reduction of deaths from perinatal asphyxia and prematurity. An increase in sepsis related deaths was observed, suggesting emphasis on infection control is key.
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    Improving Survival among Preterms: Nsambya Hospital Experience 10 Years
    (Gates Open Res, 2019) Kirabira, Victoria Nakibuuka; Nazziwa, Ritah; Sebunya, Robert; Baigana, Patrick; Nyagabyaki, Catherine; Nalunga, Sanyu; Ninsiima, Ritah; Santos, Nicole
    Surviving prematurity poses a great challenge in neonatal care in Uganda and Africa at Large and yet it remains the major cause of under-five mortality.While many preterm babies survive in high-income countries, in low- and middle-income countries lack of adequate newborn care puts the lives of many preterm babies at risk. Uganda is ranked 13th among the countries with high preterm birth deliveries worldwide.It is estimated that up to 2/3 of these deaths would be saved if secondary level interventions low cost interventions such as Kangaroo mother care (KMC), Use of antenatal steroids and Continuous positive air way Pressure, Early feeding with breast milk, use of Oxygen are scaled up.
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    Incidence and risk factors for first line anti retroviral treatment failure among Ugandan children attending an urban HIV clinic
    (AIDS research and therapy, 2013) Sebunya, Robert; Musiime, Victor; Kitaka, Sabrina Bakeera; Ndeezi, Grace
    Early recognition of antiretroviral therapy (ART) failure in resource limited settings is a challenge given the limited laboratory facilities and trained personnel. This study aimed at describing the incidence, risk factors and the resistance associated mutations (RAMs) of first line treatment failure among HIV-1-infected children attending the Joint Clinical Research Centre (JCRC), Kampala, Uganda.
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    Suboptimal glycaemic and blood pressure control and screening for diabetic complications in adult ambulatory diabetic patients in Uganda: a retrospective study from a developing country
    (Journal of Diabetes & Metabolic Disorders, 2014) Kibirige, Davis; Atuhe, David; Sebunya, Robert; Mwebaze, Raymond
    Currently, Sub Saharan Africa is faced with a substantial burden from diabetes mellitus. In most of the African countries, screening for diabetes related complications and control of blood pressure and glycaemic levels is often suboptimal. The study aimed at assessing the extent of optimal glycaemic and blood pressure control and the frequency of screening for diabetic complications in adult ambulatory Ugandan diabetic patients.