Impact of Secondary and Tertiary Neonatal Interventions on Neonatal Mortality in a Low- Resource Limited Setting Hospital in Uganda: A Retrospective Study
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Date
2022
Authors
Kirabira, Victoria Nakibuuka
Nakaggwa, Florence
Nazziwa, Ritah
Nalunga, Sanyu
Nasiima, Ritah
Nyagabyaki, Catherine
Sebunya, Robert
Latigi, Grace
Pirio, Patricia
Ahmadzai, Malalay
Journal Title
Journal ISSN
Volume Title
Publisher
BMJ open
Abstract
To assess the impact of secondary and tertiary level neonatal interventions on neonatal mortality over a period of 11 years.During the study period, a total of 25 316 neonates were admitted, of which 1853 (7.3%) died. The average inpatient mortality reduced from 8.2% during phase I to 5.7% during phase II (p=0.001). The CFR for prematurity reduced from 16.2% to 9.2% (p=0.001). There was a trend in reduction for the CFR of perinatal asphyxia from 14.9% to 13.0% (p=0.34). The CFR for sepsis had a more than a twofold increase (3%–6.8% p=0.001) between phase I and phase II. Implementation of secondary and tertiary neonatal care in resource-limited settings is feasible. This study shows that these interventions can significantly reduce the neonatal mortality, with the largest impact seen in the reduction of deaths from perinatal asphyxia and prematurity. An increase in sepsis related deaths was observed, suggesting emphasis on infection control is key.
Description
Keywords
Low- resource limited setting hospital, Impact, Secondary and tertiary neonatal interventions, Neonatal mortality
Citation
Kirabira, V. N., Nakaggwa, F., Nazziwa, R., Nalunga, S., Nasiima, R., Nyagabyaki, C., ... & Blencowe, H. (2022). Impact of secondary and tertiary neonatal interventions on neonatal mortality in a low-resource limited setting hospital in Uganda: a retrospective study. BMJ open, 12(8), e055698.http://dx.doi.org/10.1136/bmjopen-2021-055698