Browsing by Author "Ojom, Lawrence"

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    Impact of insecurity, the AIDS epidemic, and poverty on population health: disease patterns and trends in Northern Uganda.
    (The American journal of tropical medicine and hygiene, 2001) Accorsi, Sandro; Fabiani, Massimo; Lukwiya, Matthew; Ravera, Maurizio; Ojom, Lawrence; Manenti, Fabio; Anguzu, Patrick; Dente, Maria G.; Declich, Silvia
    A retrospective analysis of the discharge records of 186,131 inpatients admitted to six Ugandan hospitals during 1992–1998 was performed to describe the disease patterns and trends among the population of Northern Uganda. In all hospitals, malaria was the leading cause of admission and the frequency of admissions for malaria showed the greatest increase. Other conditions, such as malnutrition and injuries, mainly increased in the sites affected by civil conflict and massive population displacement. Tuberculosis accounted for the highest burden on hospital services (approximately one-fourth of the total bed-days), though it showed a stable trend over time. A stable trend was also observed for acquired immunodeficiency syndrome (AIDS), which is in contrast to the hypothesis that AIDS patients have displaced other patients in recent years. In conclusion, preventable and/or treatable communicable diseases, mainly those related to poverty and poor hygiene, represent the leading causes of admission and death, reflecting the socioeconomic disruption in Northern Uganda.
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    Impact of Secondary and Tertiary Neonatal Interventions on Neonatal Mortality in a Low- Resource Limited Setting Hospital in Uganda: A Retrospective Study
    (BMJ open, 2022) Kirabira, Victoria Nakibuuka; Nakaggwa, Florence; Nazziwa, Ritah; Nalunga, Sanyu; Nasiima, Ritah; Nyagabyaki, Catherine; Sebunya, Robert; Latigi, Grace; Pirio, Patricia; Ahmadzai, Malalay; Ojom, Lawrence; Nabwami, Immaculate; Burgoine, Kathy; Blencowe, Hannah
    To assess the impact of secondary and tertiary level neonatal interventions on neonatal mortality over a period of 11 years.During the study period, a total of 25 316 neonates were admitted, of which 1853 (7.3%) died. The average inpatient mortality reduced from 8.2% during phase I to 5.7% during phase II (p=0.001). The CFR for prematurity reduced from 16.2% to 9.2% (p=0.001). There was a trend in reduction for the CFR of perinatal asphyxia from 14.9% to 13.0% (p=0.34). The CFR for sepsis had a more than a twofold increase (3%–6.8% p=0.001) between phase I and phase II. Implementation of secondary and tertiary neonatal care in resource-limited settings is feasible. This study shows that these interventions can significantly reduce the neonatal mortality, with the largest impact seen in the reduction of deaths from perinatal asphyxia and prematurity. An increase in sepsis related deaths was observed, suggesting emphasis on infection control is key.