Browsing by Author "Nsadha, Zachary"

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    MorePork II project Uganda Report of the pig welfare survey in project sites
    (International Livestock Research Institute (ILRI), 2021) Nsadha, Zachary; Oba, Peter; Dione, Michel; Doyle, Rebecca
    The animal health flagship is one of the components of the project ‘Improving pig productivity and incomes through an environmentally sustainable and gender-inclusive integrated intervention package’ (MorePork II) project, which is implemented by partners of the CGIAR Research Program on Livestock (CRP Livestock) in Uganda. The focus of the animal health flagship is to contribute to the delivery of context-specific intervention packages for improving pig productivity in Uganda. As part of the animal health intervention packages for the CRP Livestock integrated project, we designed a tool to assess the current status of pig welfare in project sites. The information collected will be used to guide the design of subsequent interventions to improve overall pig welfare, herd health and productivity. Provision of facilities for domesticated pigs provides good welfare to the pigs and is a key element in pig farming. Pigs attain their fullest potential in growth and productivity if the ambience, feed and treatment provided by the farmers are adequate to meet all physiological needs. This constitutes the adequate welfare of the pig. This pig welfare survey aimed to collect data on what the farmers are providing to the pigs and identify any gaps in relation to animal welfare. The survey revealed that three pig management systems: intensive, semi-intensive and freerange, are practiced in the four project sites in Mukono and Masaka, the intervention sites and in Mpigi and Wakiso, the control sites. However, farms using the free-range system were not included in the survey because pig housing is one of the important aspects considered in the evaluation of pig welfare.
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    Tubulin vaccinated Ankole cattle develop less severe lesions than the non-vaccinated cattle when experimentally infected with Trypanosoma brucei bru
    (J Vaccines Immunol, 2020) Nanteza, Ann; Nsadha, Zachary; Namayanja, Monica; Lubega, G.William
    Invasion of the Central Nervous System (CNS) by African trypanosomes represents a critical step in the development of human African trypanosomiasis. The study aimed ats assessing the role of tubulin vaccine candidate in protection of cattle against trypanosomiasis using Trypanosoma brucei brucei subspecies that is highly related to Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense that cause sleeping sickness in man. The tissue behavior and cerebral fate of T. b. brucei in cattle should mimic the situation in humans and since cattle are also natural hosts for trypanosomes, it was envisaged that the cattle system would be a more suitable model for vaccination studies than the rodent model. Experimental infection of tubulin vaccine candidate vaccinated and non-vaccinated Ankole long horn cattle breed calves was done using a Trypanosoma brucei brucei parasite strain that had been previously isolated from naturally infected cattle in Uganda. Trypanosomiasis disease progression and associated pathology were assessed by clinical and extensive post mortem examinations. Marked organ abnormalities and severe lesions were observed in the non-vaccinated cattle, however, the findings revealed that tubulin vaccination in cattle lowers tissue parasitiasis and ameliorates the inflammatory pathology and clinical signs of trypanosomiasis by Trypanosoma brucei brucei. The trypanosome tissue invasion may be susceptible to immunological attenuation.