Browsing by Author "Nambuya, Irene"

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    Risk factors for asthma among schoolchildren who participated in a casecontrol study in urban Uganda
    (Elife, 8,, 2019) Mpairwe, Harriet; Namutebi, Milly; Nkurunungi, Gyaviira; Tumwesige, Pius; Nambuya, Irene; Mukasa, Mike; Onen, Caroline; Nnaluwooza, Marble; Apule, Barbara; Katongole, Tonny; Oduru, Gloria; Kahwa, Joseph; Webb, Emily L; Lubyayi, Lawrence; Pearce, Neil; Elliott, Alison M
    Data on asthma aetiology in Africa are scarce. We investigated the risk factors for asthma among schoolchildren (5–17 years) in urban Uganda. We conducted a case-control study, among 555 cases and 1115 controls. Asthma was diagnosed by study clinicians. The main risk factors for asthma were tertiary education for fathers (adjusted OR (95% CI); 2.32 (1.71–3.16)) and mothers (1.85 (1.38–2.48)); area of residence at birth, with children born in a small town or in the city having an increased asthma risk compared to schoolchildren born in rural areas (2.16 (1.60–2.92)) and (2.79 (1.79–4.35)), respectively; father’s and mother’s history of asthma; children’s own allergic conditions; atopy; and cooking on gas/electricity. In conclusion, asthma was associated with a strong rural-town-city risk gradient, higher parental socio-economic status and urbanicity. This work provides the basis for future studies to identify specific environmental/lifestyle factors responsible for increasing asthma risk among children in urban areas in LMICs.