Risk factors for asthma among schoolchildren who participated in a casecontrol study in urban Uganda
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Elife, 8,
Abstract
Data on asthma aetiology in Africa are scarce. We investigated the risk factors for asthma among schoolchildren (5–17 years) in urban Uganda. We conducted a case-control study, among 555 cases and 1115 controls. Asthma was diagnosed by study clinicians. The main risk factors for asthma were tertiary education for fathers (adjusted OR (95% CI); 2.32 (1.71–3.16)) and mothers (1.85 (1.38–2.48)); area of residence at birth, with children born in a small town or in the city having an increased asthma risk compared to schoolchildren born in rural areas (2.16 (1.60–2.92)) and (2.79 (1.79–4.35)), respectively; father’s and mother’s history of asthma; children’s own allergic conditions; atopy; and cooking on gas/electricity. In conclusion, asthma was associated with a strong rural-town-city risk gradient, higher parental socio-economic status and urbanicity. This work provides the basis for future studies to identify specific environmental/lifestyle factors responsible for increasing asthma risk among children in urban areas in LMICs.
Description
Keywords
asthma, schoolchildren, urban Uganda
Citation
Mpairwe, H., Namutebi, M., Nkurunungi, G., Tumwesige, P., Nambuya, I., Mukasa, M., ... & Elliott, A. M. (2019). Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda. e49496. DOI: https://doi.org/10.7554/eLife.49496