Browsing by Author "Musanje, Lawrence"

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    Biomimetic Dentin Desensitizer Based on Nano-structured Bioactive Glass
    (Dental Materials, 2011) Mitchell, John C.; Musanje, Lawrence; Ferracane, Jack L.
    This study evaluated the ability of a novel sol–gel bioactive glass, in conjunction with appropriate carrier vehicles, to reduce dentinal fluid flow, with an eye toward reducing dentinal hypersensitivity. Experiments were conducted to measure the reduction in tubule fluid flow after treatment of cut tooth surfaces with sol–gel bioactive glass particles in several carrier vehicles. Surfaces were also examined after exposure to brushing and acidic solutions. A non-bioactive particulate glass was compared. Tubular occlusion produced by the bioactive glass was observed via SEM and a sustained reduction in hydrodynamic conductance was measured after exposure to various fluids and brushing. This new material may be used with the tested carriers to significantly and durably reduce tubule fluid flow, ultimately resulting in reduced dentinal hypersensitivity.
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    Effects of resin formulation and nanofiller surface treatment on the properties of experimental hybrid resin composite
    (Biomaterials, 2004) Musanje, Lawrence; Ferracane, Jack L.
    This study evaluated the effects of nanofiller surface treatment and resin viscosity on the early and long-term properties of experimental hybrid composites. Three resin formulations (low, medium and high viscosity) were prepared by varying the ratio of TEGDMA:UDMA:bis-GMA (47:33:16wt%; 30:33:33wt%; 12:33:51wt%). Composites contained 71.3wt% silanated strontium glass (1–3μm) and 12.6wt% of either silanated or unsilanated silica (OX-50; 0.04μm). Specimens (n=10) for flexural strength, flexural modulus, fracture toughness and Knoop hardness were tested after 24h, 1 and 6 months exposure to water at 37°C. Degree of conversion (DC) was determined 24h after photoinitiation using FTIR. Resin viscosity only had a marginal influence on the mechanical response of composites but it can be adjusted to achieve a balance between DC and mechanical properties. Adding non-bonded nanofiller to hybrid composites had no systematic effect on DC. Non-bonded nanofillers had no significant effect on the long-term properties of hybrid composites.