Browsing by Author "Katusiime, Christine"

Now showing 1 - 4 of 4
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    Basis of selection of first and second line highly active antiretroviral therapy for hiv/aids on genetic barrier to resistance: a literature review.
    (African Health Sciences, 2014) Katusiime, Christine; Ocama, Ponsiano; Kambugu, Andrew
    The effectiveness of combination antiretroviral therapy (cART) continues to improve as treatment choices expand with the development of new antiretroviral agents and regimens. However, the successful long-term treatment of HIV/AIDS is under threat from the emergence of drug-resistant strains to multiple agents and entire drug classes.
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    A Case of Palatal Perforation Caused by Toxoplasmosis
    (Southern African Journal of HIV Medicine, 2010) Katusiime, Christine; Ocama, Ponsiano; Kambugu, Andrew
    HIV infection has several oral manifestations, including oral candidiasis and oral hairy leucoplakia. Occasionally unusual presentations requiring rigorous investigations are seen, and in these cases the diagnosis sometimes remains a dilemma owing to limited investigation facilities.1-3 We present the case of a patient who presented with a puzzling oral lesion.
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    Immune Reconstitution Inflammatory Syndrome among Adolescents: A Report of Cases in a Resource-Limited Setting (Uganda)
    (Southern African Journal of HIV Medicine, 2010) Katusiime, Christine; Ocama, Ponsiano; Kambugu, Andrew
    The immune reconstitution inflammatory syndrome (IRIS) is a frequent early complication of antiretroviral therapy (ART), particularly in patients who commence ART with low CD4 counts and established opportunistic infections. IRIS in HIV-infected patients results from a pathological inflammatory response to pre-existing infective, host or other antigens, alive or dead, causing clinical deterioration after initiating ART.1 The most common forms of IRIS occur in association with mycobacterial and herpesvirus infections. Adolescents and young adults comprise an increasing proportion of new HIV infections both in developing and developed countries, and little is known regarding HIV IRIS in this group. As the ART roll-out has gathered pace since 2004 in resource-limited settings, adolescent IRIS has emerged as a clinical challenge. We describe adolescent/young adult patients who presented to our clinic with IRIS events.
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    Initial description of immune reconstitution inflammatory syndrome involving the thyroid gland in an immunocompromised patient
    (Case Reports, 2011) Katusiime, Christine; Ocama, Ponsiano; Kambugu, Andrew
    Thyroid gland abscess formation is a rare occurrence owing to its inherent resistance to infections. 1 It also presents both medical and surgical dilemmas. The case we present in this report is an immune reconstitution infl ammatory syndrome (IRIS) presenting in form of a tuberculous abscess of the thyroid gland. To the best of our knowledge; this is the fi rst reported case of a paradoxical tuberculous thyroid abscess IRIS in an immunocompromised patient.