Browsing by Author "Kanyike, Andrew Marvin"
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Item Acceptance of the coronavirus disease- 2019 vaccine among medical students in Uganda(Tropical medicine and health, 2021) Kanyike, Andrew Marvin; Olum, Ronald; Kajjimu, Jonathan; Ojilong, Daniel; Madut Akech, Gabriel; Nassozi, Dianah Rhoda; Agira, Drake; Kisaakye Wamala, Nicholas; Asiimwe, Asaph; Matovu, Dissan; Nakimuli, Ann Babra; Lyavala, Musilim; Kulwenza, Patricia; Kiwumulo, Joshua; Bongomin, FelixCOVID-19 is still a major global threat for which vaccination remains the ultimate solution. Uganda reported 40,751 cases and 335 deaths as of 9 April 2021 and started its vaccination program among priority groups like health workers, teachers, those with chronic diseases among others in early March 2021. Unanimous uptake of the COVID-19 vaccine is required to subsequently avert its spread; therefore, we assessed COVID-19 vaccine acceptability, hesitancy, and associated factors among medical students in Uganda. Methods: This study employed an online descriptive cross-sectional survey among medical students across 10 medical schools in Uganda. A structured questionnaire via Google Form was conveniently sent to eligible participants via WhatsApp. Each medical school had a coordinator who consistently shared the data tool in the WhatsApp groups. Chi-square or Fisher’s exact test, and logistic regression were used to assess the association between vaccine acceptability with demographics, COVID-19 risk perception, and vaccine hesitancy. Results: We surveyed 600 medical students, 377 (62.8%) were male. COVID-19 vaccine acceptability was 37.3% and vaccine hesitancy 30.7%. Factors associated with vaccine acceptability were being male (adjusted odds ratio (aOR) = 1.9, 95% CI 1.3–2.9, p=0.001) and being single (aOR= 2.1, 95% CI 1.1–3.9, p=0.022). Very high (aOR= 3.5, 95% CI 1.7– 6.9, p<0.001) or moderate (aOR =2.2, 95% CI 1.2–4.1, p=0.008) perceived risk of getting COVID-19 in the future, receiving any vaccine in the past 5 years (aOR= 1.6, 95% CI 1.1–2.5, p=0.017), and COVID-19 vaccine hesitancy (aOR 0.6, 95% CI 0.4–0.9, p=0.036). Conclusions: This study revealed low levels of acceptance towards the COVID-19 vaccine among medical students, low self-perceived risks of COVID-19, and many had relied on social media that provided them with negative information. This poses an evident risk on the battle towards COVID-19 in the future especially when these future health professions are expected to be influencing decisions of the general public towards the same.Item Antimicrobial resistance and rational prescription practices: knowledge, perceptions and confidence of health profession interns in Uganda(JAC-Antimicrobial Resistance, 2023-10-03) Nabidda, Shamim; Ssennyonjo, Rogers; Atwaru, Joseph; Kanyike, Andrew Marvin; Baryayaka, Shiellah; Tusiimire, JonansAntimicrobial resistance (AMR) is significantly driven by misuse and overuse of antibiotics. Graduate health profession interns often prescribe antimicrobials under minimum supervision. This study explored the knowledge, perceptions and confidence of health profession interns in Uganda regarding AMR and rational prescription practices. This was a cross-sectional survey employing quantitative techniques carried out between October and November 2022 at six tertiary hospitals in Uganda. Health profession interns including doctors, nurses, midwives and pharmacists were recruited as study participants. Data were collected using online Kobo toolbox software. Data analysis was performed using STATA (StataCorp) version 16. Bivariate analysis and multivariable logistic regression were performed. P < 0.05 was considered statistically significant. We recruited 281 participants with a mean age of 27 ± 3.8 years, of which few (n = 53; 19%) had good knowledge about AMR and rational prescription. The use of professional organization guidelines as a source of information was significantly associated with good knowledge (adjusted OR = 1.9; 95% CI: 1.0–3.5; P = 0.046). Nurses had the least knowledge compared with doctors and pharmacists. Continuous medical education (99%) and availability of clinical guidelines (98%) were identified as the most helpful intervention to improve knowledge. Most participants were confident about accurately diagnosing infections and sepsis and selecting appropriate antimicrobials. Continuous medical education and availability of clinical and professional organization guidelines should be leveraged to improve the knowledge of AMR and rational prescription among health profession interns. Their high confidence in rational prescription practices should be pivotal to the fight against AMR.Item Antimicrobial resistance and rational use of medicine: knowledge, perceptions, and training of clinical health professions students in Uganda(Research Square, 2022) Kanyike, Andrew Marvin; Olum, Ronald; Kajjimu, Jonathan; Owembabazi, Shebah; Ojilong, Daniel; Nassozi, Dianah Rhoda; Amongin, Joan Fidelia; Atulinda, Linda; Agaba, Kenneth; Buule, Richard; Nabukeera, Germinah; Kyomuhendo, Robert; Luwano, Rehema; Owobusingye, Whitney; Matovu, Dissan; Musoke, Philip; Bongomin, Felix; Kiyimba, KenedyAntimicrobial resistance (AMR) is an important global health concern, projected to contribute to significant mortality, particularly in developing countries. This study aimed to determine the knowledge, perceptions of clinical health professions students towards antimicrobial resistance and rational use of medicine and confidence level to prescribe antimicrobials. Methods: An online descriptive cross-sectional survey was conducted among clinical health professions students across 9 medical schools in Uganda. A semi-structured questionnaire using Kobo Toolbox form was shared among participants via WhatsApp Messenger (Meta, California, USA). Knowledge was categorized using modified Bloom’s cut-off. One-way ANOVA, Chi-square or Fisher’s exact test, and logistic regression were used to assess the association between dependent and independent variables. A p<0.05 was considered statistically significant. Results: We surveyed 681 participants, most were pursuing a Bachelor of Medicine and Surgery degree (n=433, 63.6%), with a mean age of 24 (standard deviation: 3.6) years. Most participants (n=596, 87.5%) had sufficient knowledge about antimicrobial resistance with a mean score of 85 ± 14.2%. There was a significant difference in mean knowledge scores of year 4 (86.6%) compared to year 3 (82.4%) (p=0.002) and year 5 (88.0%) compared to year 3 (82.4%) (p<0.001). Most participants (n=456, 66.9%), were confident on making an accurate diagnosis of infection, and choosing the correct antimicrobial agent to use (n=484, 71.1%). Conclusion: Health profession students exhibited good knowledge on antimicrobial resistance and high self-perceived confidence on antimicrobial prescriptions however they still agreed that a separated course unit on AMR is necessary.Item COVID-19 Vaccination Uptake and Self-Reported Side Effects among Healthcare Workers in Mbale City Eastern Uganda(medRxiv, 2022) Madut Akech, Gabriel; Kanyike, Andrew Marvin; Galabuzi Nassozi, Ashah; Aguti, Beatrice; Nakawuki, Ashley Winfred; Kimbugwe, Denis; Kiggundu, Josen; Maiteki, Robert; Mukyala, Dorothy; Bongomin, Felix; Obakiro, Samuel Baker; Nekaka, Rebecca; Iramiot, Jacob StanleyFear of anticipated side effects has hindered the COVID-19 vaccination program globally. We report the uptake and the self-reported side effects (SEs) of the COVID-19 vaccine among Healthcare workers (HCWs) in Mbale City Eastern Uganda. Methods: A cross-sectional survey of HCWs at seven different level health facilities was conducted from 6th September to 7th October 2021 using a structured self-administered questionnaire. Results: COVID-19 vaccine had been received by 119 (69%) participants of which 79 (66%) received the two recommended doses of the AstraZeneca vaccine. Getting vaccinated was associated with working in a lower health facility (aOR= 14.1, 95% CI: 4.9 – 39.6, P=0.000), perceived minor risk of contracting COVID-19 (aOR= 12.3, 95% CI: 1.0 – 44.6, p=0.047), and agreeing that COVID-19 vaccine is protective (aOR= 16.7, 95% CI: 5.6 – 50.4, p=0.000). 97 (82%) of participants experienced side effects to at least one dose of which most were mild on both the first (n=362, 51%) and second dose (n=135, 69%). The most frequently reported side effects on the first and second dose were fever (79% and 20%), injection site pain (71% and 25%), and Fatigue (69% and 20%) respectively. Conclusions: The majority of the HCWs in Mbale City had received at least one dose of the COVID-19 vaccine and experienced a side effect. The side effects were mostly mild on either dose thus the vaccines are generally safe.Item Factors Associated with Medical Students’ Career Choices Regarding Internal Medicine in Uganda(Research Square, 2022) Bongomin, Felix; Olum, Ronald; Kajjimu, Jonathan; Kanyike, Andrew Marvin; Atulinda, Linda; Ninsiima, Daphine; Kisaakye Wamala, Nicholas; Byakika-Kibwika, PaulineThere is an unmet need for internal medicine physicians in Uganda owing to the growing burden of diseases. This study aimed at evaluating the factors associated with career choices of undergraduate medical students regarding internal medicine in Uganda. Methods We conducted a cross-sectional study in the first 3 weeks of October 2021 via WhatsApp messenger. Medical students in the 3rd to 5th year of study who had completed internal medicine clinical rotations and pursuing a Bachelor of Medicine and Bachelor of Surgery (MBChB) degree at 7 Ugandan universities (4 public and 3 private) were enrolled. Multivariable logistic regression model was constructed to determine factors associated with a career choice in internal medicine. Results We enrolled 418 participants, median age 24 (interquartile range (IQR): 23 – 26) years, 67.7% were male, and 36.1% had a family member or relative who was a doctor. Most of the students (84.0%) were interested in research. The top three most preferred specialties were internal medicine (52.6%), surgery (51.2%), and obstetrics & gynaecology (51.0%). Overall, 186 (44.5%) participants reported plans to pursue a Master of Medicine degree in internal medicine. Interest in research was the only factor independently associated with 2.5-fold higher odds of pursuing a career in internal medicine (adjusted odds ratio: 2.5, 95% CI: 1.4 — 4.6, p=0.003). About 73% of the participants strongly agreed that internal medicine requires wide reading. Conclusions There is strong interest to pursue a career in internal medicine among Ugandan medical students. We recommend increase in training opportunities in Internal Medicine especially in view of the growing disease burden and increasing population growth.Item Fear of COVID-19 and the Media Influence on Herbal Medication Use in Uganda: A Cross-Sectional Study(Risk Management and Healthcare Policy, 2021) Musoke, Phillip; Nantaayi, Brandy; Kato Ndawula, Rodney; Wannyana, Babrah; Ssewante, Nelson; Wekha, Godfrey; Olum, Ronald; Nakyagaba, Lourita; Nassozi, Dianah Rhoda; Nabukeera, Germinah; Kanyike, Andrew Marvin; Ojilong, Daniel; Madut Akech, Gabriel; Kajjimu, Jonathan; Kiwumulo, Joshua; Agira, Drake; Okot, Jerom; Bongomin, FelixThe coronavirus disease-2019 (COVID-19) pandemic has created fear in people around the world. This has led to the widespread use of various herbal remedies in its prevention and treatment regardless of the paucity of scientific evidence about their safety and efficacy. This study assessed the fear of COVID-19 and the influence of media on the use of herbal medicine to prevent or treat COVID-19 in Uganda. Methods: In the first 2 weeks of July 2021, a descriptive online cross-sectional study was carried out anonymously in the general population in Uganda. A validated questionnaire was used to collect data on herbal medicine use and the influence of media. Fear of COVID-19 was rated using the Fear of COVID-19 Scale (FCV-19S). Results: We recruited 488 participants, 273 (55.9%) were female, with a median age of 25 (range: 18–73) years. Sixty-seven (57.8%) participants had a confirmed COVID-19 diagnosis. The mean FCV-19S score was 21.7 SD 5.9 with 53.3% reporting high levels of COVID-19 fear. About 57.4% of participants reported using herbal remedies either to prevent or treat COVID-19-like symptoms. Media was the main source of information, with more than 80% of the participants reporting seeing or accessing information about herbal medication use. Women (adjusted odds ratio (aOR): 1.74, 95% CI: 1.2–2.5, p=0.003) and people with a previously confirmed COVID-19 diagnosis (aOR: 3.1, 95% CI: 1.35–7.14, p=0.008) had a statistically significantly higher FCV-19S score. Being unemployed (aOR: 1.0, 95% CI: 1.1–2.3, p=0.008) and a female (aOR: 1.0, 95% CI: 1.1–2.3, p=0.012) were statistically significantly associated with herbal medicine use. Participants who used herbal remedies had a higher median FCV-19S score compared to non-users (23 versus 21, p<0.001). Conclusion: The use of herbal medicines to treat or prevent COVID-19 is a widespread practice among the general population in Uganda amidst the high levels of fear of COVID-19.Item Perspective of Medical Students on the COVID-19 Pandemic: Survey of Nine Medical Schools in Uganda(JMIR public health and surveillance, 2020) Olum, Ronald; Kajjimu, Jonathan; Kanyike, Andrew Marvin; Chekwech, Gaudencia; Wekha, Godfrey; Nassozi, Dianah Rhoda; Kemigisa, Juliet; Mulyamboga, Paul; Kabagambe Muhoozi, Oscar; Nsenga, Lauryn; Lyavala, Musilim; Asiimwe, Asaph; Bongomin, FelixThe coronavirus disease (COVID-19) pandemic is a global public health concern affecting over 5 million people and posing a great burden on health care systems worldwide. Objective: The aim of this study is to determine the knowledge, attitude, and practices of medical students in Uganda on the COVID-19 pandemic. Methods: We conducted an online, descriptive cross-sectional study in mid-April 2020, using WhatsApp Messenger. Medical students in 9 of the 10 medical schools in Uganda were approached through convenience sampling. Bloom’s cut-off of 80% was used to determine good knowledge (≥12 out of 15), positive attitude (≥20 out of 25), and good practice (≥12 out of 15). Results: The data of 741 first- to fifth-year medical students, consisting of 468 (63%) males with a mean age of 24 (SD 4) years, were analyzed. The majority (n=626, 84%) were pursuing Bachelor of Medicine and Bachelor of Surgery degrees. Overall, 671 (91%) had good knowledge, 550 (74%) had a positive attitude, and 426 (57%) had good practices. Knowledge was associated with the 4th year of study (adjusted odds ratio [aOR] 4.1, 95% CI 1.6-10.3; P<.001). Attitude was associated with the female sex (aOR 0.7, 95% CI 0.5-1; P=.04) and TV or radio shows (aOR 1.1, 95% CI 0.6-2.1; P=.01). Practices were associated with the ≥24 years age category (aOR 1.5, 95% CI 1.1-2.1; P=.02) and online courses (aOR 1.8, 95% CI 1.1-3.2; P=.03). In total, 592 (80%) medical students were willing to participate in frontline care if called upon. Conclusions: Medical students in Uganda have sufficient knowledge of COVID-19 and will be a large reservoir for health care response when the need arises.Item Treatment of COVID-19 with Herbal Medicines: Perceptions, Attitudes and Practices of Healthcare Professionals Students in Uganda(ResearchSquare, 2021) Kiyimba, Blaise; Kanyike, Andrew Marvin; Ssewante, Nelson; Musoke, Phillip; Atulinda, Linda; Namuwaya, Claire; Wamala, Nicholas Kisaakye; Onyait, Teddy; Aringo, Ramona Noeline; Kato, Hussein; Asasira, Ignatius; Bongomin, FelixUse of herbal medicine (HM) for the treatment and prevention of the coronavirus disease -2019 (COVID19) has been reported worldwide. In this study, we aimed to assess the perceptions, attitude and practices of healthcare professionals (HP) students in Uganda concerning HM use in the management of COVID-19 illnessItem Treatment of COVID-19 with Herbal Medicines: Perceptions, Attitudes and Practices of Healthcare Professionals Students in Uganda(PMC, 2021-09-14) Kiyimba, Blaise; Kanyike, Andrew Marvin; Kato, Hussein; Asasira, Ignatius; Bongomin, FelixUse of herbal medicine (HM) for the treatment and prevention of the coronavirus disease -2019 (COVID-19) has been reported worldwide. In this study, we aimed to assess the perceptions, attitude and practices of healthcare professionals (HP) students in Uganda concerning HM use in the management of COVID-19 illness.