Browsing by Author "Easterbrook, Philippa J."

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    The Challenge of HIV-1 Antiretroviral Resistance in Africa in the Era of HAART
    (AIDS reviews, 2009) Sendagire, Hakim; Easterbrook, Philippa J.; Nankya, Immaculate; Arts, Eric; Thomas, David; Reynolds, Steven J.
    Antiretroviral therapy programs in Africa are currently providing treatment for almost two million people. The long-term success of large scale antiretroviral therapy programs in sub-Saharan Africa remains uncertain because of the limited information currently available on rates of virologic failure and selection for drug-resistant variants in the different HIV subtypes. This article provides a comprehensive review of the published literature on the prevalence of primary and secondary HIV drug resistance with different subtypes and in various settings across sub-Saharan Africa.