The Challenge of HIV-1 Antiretroviral Resistance in Africa in the Era of HAART

Abstract
Antiretroviral therapy programs in Africa are currently providing treatment for almost two million people. The long-term success of large scale antiretroviral therapy programs in sub-Saharan Africa remains uncertain because of the limited information currently available on rates of virologic failure and selection for drug-resistant variants in the different HIV subtypes. This article provides a comprehensive review of the published literature on the prevalence of primary and secondary HIV drug resistance with different subtypes and in various settings across sub-Saharan Africa.
Description
Keywords
Antiretroviral therapy, ART, Resistance, Africa, Subtypes, Phenotypic, Genotypic
Citation
Sendagire, H., Easterbrook, P. J., Nankya, I., Arts, E., Thomas, D., & Reynolds, S. J. (2009). The challenge of HIV-1 antiretroviral resistance in Africa in the era of HAART. AIDS reviews, 11(2), 59.