Browsing by Author "Ayuba, John Tabakwot"

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    COVID-19-Related Mental Health Burden and Reduced Awareness of Mental Healthcare Services in Low Income Earners of Western Uganda
    (ResearchSquare, 2020) Lemuel, Ann Monima; Kasozi, Kenneth Iceland; Bassey, Victor Archibong; Ssebuufu, Robinson; Aruwa, Joshua Ojodale; Odoma, Saidi; Ssempijja, Fred; Ayuba, John Tabakwot; Kembabazi, Stellamaris; Nankya, Viola; Matama, Kevin
    The imposed COVID-19 lockdown is taking a toll on mental health individuals, with lowincome earners considered most affected, as the imposed lockdown was accompanied with partial or complete loss of livelihood among low income earners. The study aimed to investigate level of education and relationship status on awareness of mental healthcare and explore how these factors influence mental health among low income earners in Western Uganda. A cross sectional descriptive study was undertaken among low-income earners in South Western Uganda. Data were collected from two hundred and fifty-three (253) participants using a structured closed ended questionnaire. Anxiety, anger and depression were assessed using a modified generalized anxiety disorder (GAD-7), Spielberger’s State-Trait Anger Expression Inventory-2 (STAXI-2) and Beck Depression Inventory (BDI) item tools respectively. Most respondents were single male individuals with secondary level of education. Respondents with tertiary level of education and those with partners had higher score (71.7% and 70.28% respectively) for awareness on mental healthcare. Respondents with primary education level and individuals that were single had higher score (46.98% and 43.72% respectively) for anxiety. Respondents with primary education level and those living with partners had higher mean score (56.44% and 56.21% respectively) for anger. Respondents with no formal education and those who had lost partners had higher mean score (32.11% and 30.50% respectively) for depression. Individuals without formal educational and primary education were observed to have a negative correlation (r2 = 47.4 and 6.4% respectively) with awareness on mental healthcare, and the no formal group had positive correlation with anger and depression (r2 =1.9 and 0.3% respectively), while other groups were negatively correlated (r2 =10.1%). The group of single individuals had a negative correlation with awareness on mental healthcare, anger and depression (r2 =1.9, 0.8 and 0.3% respectively), and a positive correlation with anxiety (r2 =3.9%). It is evident that education and relationship status influence awareness on mental healthcare and mental health state among low income earners in Western Uganda. Therefore, we suggest policy maker pay more attention to social transformation, through proper engagement of low income earners.
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    COVID-19-Related Mental Health Burdens: Impact of Educational Level and Relationship Status Among Low-Income Earners of Western Uganda
    (Frontiers in public health, 2021) Lemuel, Ann Monima; Alghamdi, Saad; Archibong, Victor; Kasozi, Keneth Iceland; Ssebuufu, Robinson; Kabanyoro, Annet; Swase, Dominic Terkimbi; Ssempijja, Fred; Ayuba, John Tabakwot; Matama, Kevin; Kembabazi, Stellamaris; Kairania, Emmanuel; Batiha, Gaber El-Saber; Welburn, Susan Christina
    The study aimed to investigate the relationship between mental health with the level of education, relationship status, and awareness on mental health among low-income earners in Western Uganda. This was a cross-sectional descriptive study carried out among 253 participants. Anxiety, anger, and depression were assessed using a modified generalized anxiety disorder (GAD-7), Spielberger's State-Trait Anger Expression Inventory-2, and Beck Depression Inventory item tools, respectively. The majority of our respondents were male (n = 150/253, 59.3), had a secondary level of education (104/253, 41.1), and were single (137/253, 54.2). No formal education and primary education (r2 = 47.4% and 6.4%, respectively) had a negative correlation with awareness of mental health care. In addition, no formal education had a positive correlation with anger and depression (r2 = 1.9% and 0.3%, respectively). Singleness in this study had a negative correlation with awareness of mental health care, anger, and depression (r2 = 1.9, 0.8, and 0.3%, respectively), and a positive correlation with anxiety (r2 = 3.9%). It is evident that education and relationship status influenced awareness on mental health care and mental health state among low-income earners in Western Uganda during the first COVID-19 lockdown. Therefore, policymakers should strengthen social transformation through the proper engagement of low-income earners in this COVID-19 era.
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    Galinsoga parviflora restored associated motor coordination through increased linear distribution of Purkinje Cells in mercury chloride-induced toxicity of mice’s cerebellum
    (African Journal of Cellular Pathology, 2022) Ayuba, John Tabakwot; Ayodeji Okesina, Akeem; Ibe, Michael Usman; Kunle Ajenikoko, Michael; Theophilus, Pius; Kusiima, Nicholas; Odoma, Saidi; Edgar, Mario Fernandez
    Mercury (Hg) is a poisonous substance associated with diseases, such as ataxia and Joubert syndrome. Therefore, it is important to find a way to disrupt the process of Hg poisoning in the cerebellum, by exploring the medicinal value of local herb such as Galinsoga parviflora (GP). This study examined the effects of aqueous leaf extract of GP in HgCl2-induced cerebellar toxicity in adult male mice. Twenty-five adult male mice of an average weight of 25 g were randomly divided into 5 groups (n=5). Animals in Group I received oral administration of 2 ml/kg distilled water for 6 weeks, Group II received 2.3 mg/kg of HgCl2 for 3 weeks, Group III received 2.3 mg/kg of HgCl2 for the first 3 weeks followed by oral administration of 800mg/kg of GP extract for the next 3 weeks, Group IV received 800mg/kg of GP extract for the first 3 weeks followed by 2.3 mg/kg of HgCl2 for the next three weeks, and Group V received 2.3 mg/kg of HgCl2 and 800 mg/kg of GP extract concurrently for three weeks. The test animals were subjected to beam walking tests during the experiment period, followed by euthanasia, perfusion fixation, and tissue sample collection for histological and histochemical analysis. Treatment with the extract of GP showed varying degrees of regeneration in the cerebellar Purkinje cells and myelin sheath of mice in HgCl2 induced toxicity, with corresponding improvements in balance and posture. Cerebellar HgCl2 exposure in the present study was neurotoxic; however, treatment with GP was of therapeutic value.
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    Impact of COVID-19 Pandemic on the Mental Health of Sports Fans
    (Research Square, 2020) Ayuba, John Tabakwot; Kasozi, Keneth Iceland; Ssempijja, Fred; Ssebuufu, Robinson; Saidi, Odoma; Matama, Kevin
    Information regarding COVID-19 mental health burden among medical workers and other vulnerable individuals has been hugely emphasized during the stressful campaign against COVID-19, however, the mental health problems among sports fans and athletes of Africa and globally have been neglected. The present studies investigated mental health burden and knowledge of sport associated with mental health issues among sports fans.