The National Research Repository of Uganda - NRU

Welcome to the National Research Repository of Uganda, abbreviated as "NRU". NRU was established in 2021. NRU is a collection of scholarly output by researchers from the UNCST Community, including scholarly articles and books, electronic theses and dissertations, conference proceedings, journals, technical reports and digitised library collections. It is the official Institutional Archive (IA) of UNCST.

For information about the publishers' copyright policy on archiving your articles online or in an institutional archive, visit the Sherpa Site at http://www.sherpa.ac.uk/romeo.php The site gives a summary of the permissions normally given as part of each publisher's copyright transfer agreement. If you wish to publish your research findings in the NRU, please contact NRU administrator at admin@uncst.go.ug for details. NRU operates both open access and closed access models. Access to fulltext has been restricted in adherence to the UNCST Intellectual Property Rights (IPR) and Copyrights policies.

Other Useful Resources:

Africa Portal is an online repository of open access library collection with over 3,000 books, journals, and digital documents on African policy issues. This is an initiative by the Centre for International Governance Innovation (CIGI), Makerere University (MAK), and the South African Institute of International Affairs (SAIIA). Please visit the Africa Portal at http://www.africaportal.org/library.

Communities in NRU

Select a community to browse its collections.

Now showing 1 - 5 of 9

Books and Book Abstracts
This community contains Open Access Books and Book Abstracts
Conference Proceedings
This community contains Ugandan Conference proceedings
Institutional Annual Research Reports
This community contains consolidated Ugandan Institutional Annual Research Reports on a broad range of subjects
Institutional Repository Policies
This community contains approved and running institutional repository policies from different research institutions
Journal Publications
This community contains Open access peer reviewed publications about Uganda and from Ugandan Researchers. The community has been classified to thematic research sub communities of Agricultural Sciences, Engineering and Technology, Humanities, Medical and Health Sciences, Natural Sciences and Social Sciences.

Recent Submissions

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Rehabilitation and Reintegration Programming adjunct to Female Genital Fistula Surgery: a scoping review protocol

(BMJ open, 2019-09-25) El Ayadi,Alison M; Obore, Susan; Byamugisha, Josaphat; Barageine, Justus K

Female genital fistula is a debilitating traumatic injury, largely birth-associated, globally affecting up to 2 million women, mostly in sub-Saharan Africa. Fistula has significant physical, psychological and economic consequences. Women often face challenges in reintegrating and resuming prior roles despite successful surgery. Synthesising the evidence on services adjunct to fistula surgery and their outcomes is important for developing the evidence base for best practices and identifying research priorities. This scoping review seeks to examine the range of rehabilitation and reintegration services provided as adjunct to genital fistula surgery, map the existing programming and outcomes, and identify areas for additional research.

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Effect of Preoperative Bicarbonate Infusion on Maternal and Perinatal Outcomes of Obstructed Labour in Mbale Regional Referral Hospital: a study protocol for a randomised controlled trial

(BMJ open, 2019-02-28) Musaba, Milton W.; Barageine, Justus K.; Ndeezi, Grace; Wandabwa, Julius N.; Andrew, Weeks

To improve maternal and fetal outcomes among patients with obstructed labour (OL) in low-resource settings, the associated electrolyte and metabolic derangements must be adequately corrected. Oral fluid intake during labour and preoperative intravenous fluid replacement following OL corrects the associated dehydration and electrolyte changes, but it does not completely reverse the metabolic acidosis, that is, a cause of intrapartum birth asphyxia and a risk factor for primary postpartum haemorrhage due to uterine atony. Sodium bicarbonate is a safe, effective, cheap and readily available acid buffer, that is widely used by sportspeople to improve performance. It also appears to improve fetal and maternal outcomes in abnormally progressing labour. However, its effects on maternal and fetal outcomes among patients with OL is unknown. We aim at establishing the effect of a single-dose preoperative infusion of sodium bicarbonate on maternal and fetal lactate levels and clinical outcomes among patients with OL.

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Estimating the Cost and Cost-effectiveness for Obstetric Fistula Repair in Hospitals in Uganda: a Low Income Country

(Health Policy and Planning, 2018-09-24) Epiu, Isabella; Alia, Godfrey; Mukisa, John; Mohammed, Lamorde; Andreas, Kuznik

In Africa, about 33 000 cases of obstetric fistula occur each year. Women with fistula experience debilitating incontinence of urine and/or faeces and are often socially ostracized. Worldwide, Uganda ranks third among countries with the highest burden of obstetric fistula. Obstetric fistula repair competes for scarce resources with other healthcare interventions in resource-limited settings, even though it is surgically efficacious. There is limited documentation of its cost-effectiveness in the most affected settings. We therefore sought to assess the cost-effectiveness of surgical intervention for obstetric fistula in Uganda so as to provide appropriate data for policy-makers to prioritize fistula repair and reduce women’s suffering in similarly burdened countries. We built a decision-analytic model from the perspective of Uganda’s National Health System to estimate the cost-effectiveness of vesico-vaginal and recto-vaginal fistula surgery vs a competing strategy of no surgery for Ugandan women with fistula. Long-term disability outcomes were assessed based on a lifetime Markov state-transition cohort and effectiveness of surgery. Surgical costs were estimated by micro-costing local Ugandan health resources. Disability weights associated with vesico-vaginal, recto-vaginal fistula and mortality rates among the general population in Uganda were based on published sources. The cost of providing fistula repair surgery in Uganda was estimated at $378 per procedure. For a hypothetical 20-year-old woman, surgery was estimated to decrease the lifetime disability burden from 8.53 DALYs to 1.51 DALYs, yielding a cost per DALY averted of $54. The results were robust to variations in model inputs in one-way and probabilistic sensitivity analyses. Surgery for obstetric fistula appears highly cost-effective in Uganda. In similar low-income countries, governments and non-governmental organizations need to prioritize training and strengthening surgical capacity to increase access to fistula surgical care, which would be an important step towards achieving universal health coverage.

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Perceived Causes of Obstetric Fistula and Predictors of Treatment Seeking among Ugandan Women: Insights from Qualitative Research

(African journal of reproductive health, 2020-07-24) Nalubwama, Hadija; El Ayadi, Alison M.; Barageine, Justus K.; Byamugisha, Josaphat; Kakaire, Othman; Obore, Susan; Mwanje, Haruna; Miller, Suellen

Many obstetric fistula patients remain untreated or present late to treatment despite increasing surgical availability in Uganda. We explored women‘s perceptions of the cause of their obstetric fistula and their treatment seeking behaviours, including barriers and facilitators to timely care access. In-depth interviews and focus group discussions were conducted from June–August 2014 among 33 women treated for obstetric fistula at Mulago Hospital, Kampala. Data were analysed to describe dimensions and commonalities of themes identified under perceived causes and treatment seeking experiences, and their intersection. Perceived obstetric fistula causes included delays in deciding on hospital delivery, lengthy labour, injury caused by the baby, health worker incompetence, and traditional beliefs. Treatment seeking timing varied. Early treatment seeking was facilitated by awareness of treatment availability through referral, the media, community members, and support by partners and children. Barriers to early treatment seeking included inadequate financial and social support, erroneous perceptions about fistula causes and curability, incorrect diagnoses, and delayed or lack of care at health facilities. Our study supports broad educational and awareness activities, facilitation of social and financial support for accessing care, and improving the quality of emergency obstetric care and fistula treatment surgical capacity to reduce women‘s suffering.

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Prevalence and Factors Associated with Second Trimester Pregnancy Loss among Women Admitted at a National Referral Hospital in Uganda: a cross-sectional study

(African Health Sciences, 2025-01-11) Irumba, Charles; Kaye, Dan K.; Barageine, Justus K.; Ampwera,Rodgers; Atwiine, Hope

Second trimester pregnancy loss (abortion) refers to induced or spontaneous termination of pregnancy from 13 to the end of 26 weeks of gestation. Second trimester abortions contribute to a high proportion of maternal morbidity, mortality and psychological stress especially in low-resource countries with restricted access to safe abortion services. While globally, the prevalence of second trimester abortions is 10–15%, the prevalence at Kawempe National Referral Hospital was not known. The study objective was to determine the prevalence and factors associated with second trimester abortion at Kawempe National Referral Hospital.