Germinal Matrix-Intraventricular Hemorrhage: A Tale of Preterm Infants

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dc.contributor.authorEgesa, Walufu Ivan
dc.contributor.authorOdoch, Simon
dc.contributor.authorOdong, Richard Justin
dc.contributor.authorNakalema, Gloria
dc.contributor.authorAsiimwe, Daniel
dc.contributor.authorEkuk, Eddymond
dc.contributor.authorTwesigemukama, Sabinah
dc.contributor.authorTuryasiima, Munanura
dc.contributor.authorLokengama, Rachel Kwambele
dc.contributor.authorWaibi, William Mugowa
dc.contributor.authorAbdirashid, Said
dc.contributor.authorKajoba, Dickson
dc.contributor.authorKumbakulu, Patrick Kumbowi
dc.date.accessioned2023-04-12T16:43:02Z
dc.date.available2023-04-12T16:43:02Z
dc.date.issued2021
dc.description.abstractGerminal matrix-intraventricular hemorrhage (GM-IVH) is a common intracranial complication in preterm infants, especially those born before 32 weeks of gestation and very-low-birth-weight infants. Hemorrhage originates in the fragile capillary network of the subependymal germinal matrix of the developing brain and may disrupt the ependymal lining and progress into the lateral cerebral ventricle. GM-IVH is associated with increased mortality and abnormal neurodevelopmental outcomes such as posthemorrhagic hydrocephalus, cerebral palsy, epilepsy, severe cognitive impairment, and visual and hearing impairment. Most affected neonates are asymptomatic, and thus, diagnosis is usually made using real-time transfontanellar ultrasound. The present review provides a synopsis of the pathogenesis, grading, incidence, risk factors, and diagnosis of GM-IVH in preterm neonates. We explore brief literature related to outcomes, management interventions, and pharmacological and nonpharmacological prevention strategies for GM-IVH and posthemorrhagic hydrocephalus.en_US
dc.identifier.citationEgesa, W. I., Odoch, S., Odong, R. J., Nakalema, G., Asiimwe, D., Ekuk, E., ... & Kumbakulu, P. K. (2021). Germinal matrix-intraventricular hemorrhage: a tale of preterm infants. International Journal of Pediatrics, 2021.https://doi.org/10.1155/2021/6622598en_US
dc.identifier.urihttps://nru.uncst.go.ug/handle/123456789/8444
dc.language.isoenen_US
dc.publisherInternational Journal of Pediatricsen_US
dc.subjectPreterm Infantsen_US
dc.subjectGerminal Matrix-Intraventricular Hemorrhageen_US
dc.titleGerminal Matrix-Intraventricular Hemorrhage: A Tale of Preterm Infantsen_US
dc.typeArticleen_US
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