Effect of SARS-CoV-2 Infection in Pregnancy on Maternal and Neonatal Outcomes in Africa: An AFREhealth Call for Evidence through Multicountry Research Collaboration

Simple item page
dc.contributor.authorNachega, Jean B.
dc.contributor.authorAgudu, Nadia A. Sam
dc.contributor.authorBudhram, Samantha
dc.contributor.authorTaha, Taha E.
dc.contributor.authorVannevel, Valerie
dc.contributor.authorSomapillay, Priya
dc.contributor.authorIshoso, Daniel Katuashi
dc.contributor.authorPipo, Michel Tshiasuma
dc.contributor.authorNswe, Christian Bongo-Pasi
dc.contributor.authorDitekemena, John
dc.contributor.authorAyele, Birhanu T.
dc.contributor.authorMachekano, Rhoderick N.
dc.contributor.authorGachuno, Onesmus W.
dc.contributor.authorKinuthia, John
dc.contributor.authorMwongeli, Nancy
dc.contributor.authorSekikubo, Musa
dc.contributor.authorMusoke, Philippa
dc.contributor.authorAgbeno, Evans Kofi
dc.contributor.authorUmar, Lawal W.
dc.contributor.authorNtakwinja, Mukanire
dc.contributor.authorMukwege, Denis M.
dc.contributor.authorSmith, Emily R.
dc.contributor.authorMills, Eduard J.
dc.contributor.authorOtshudiema, John Otokoye
dc.contributor.authorKingebeni, Placide Mbala
dc.contributor.authorKayembe, Jean-Marie N.
dc.contributor.authorLandu, Don Jethro Mavungu
dc.contributor.authorTamfum, Jean-Jacques Muyembe
dc.contributor.authorZumla, Alimuddin
dc.contributor.authorLangenegger, Eduard J.
dc.contributor.authorMofenson, Lynne M.
dc.date.accessioned2022-01-29T07:52:54Z
dc.date.available2022-01-29T07:52:54Z
dc.date.issued2021
dc.description.abstractIn the African context, there is a paucity of data on SARS-CoV-2 infection and associated COVID-19 in pregnancy. Given the endemicity of infections such as malaria, HIV, and tuberculosis (TB) in sub-Saharan Africa (SSA), it is important to evaluate coinfections with SARS-CoV-2 and their impact on maternal/infant outcomes. Robust research is critically needed to evaluate the effects of the added burden of COVID-19 in pregnancy, to help develop evidence-based policies toward improving maternal and infant outcomes. In this perspective, we briefly review current knowledge on the clinical features of COVID-19 in pregnancy; the risks of preterm birth and cesarean delivery secondary to comorbid severity; the effects of maternal SARS-CoV-2 infection on the fetus/neonate; and in utero mother-to-child SARS-CoV-2 transmission. We further highlight the need to conduct multicountry surveillance as well as retrospective and prospective cohort studies across SSA. This will enable assessments of SARS-CoV-2 burden among pregnant African women and improve the understanding of the spectrum of COVID-19 manifestations in this population, which may be living with or without HIV, TB, and/or other coinfections/comorbidities. In addition, multicountry studies will allow a better understanding of risk factors and outcomes to be compared across countries and subregions. Such an approach will encourage and strengthen much-needed intra-African, south-to-south multidisciplinary and interprofessional research collaborations. The African Forum for Research and Education in Health’s COVID-19 Research Working Group has embarked upon such a collaboration across Western, Central, Eastern and Southern Africa.en_US
dc.identifier.citationNachega, J. B., Sam-Agudu, N. A., Budhram, S., Taha, T. E., Vannevel, V., Somapillay, P., ... & AFREhealth COVID-19 Research Collaboration Working Group. (2021). Effect of SARS-CoV-2 infection in pregnancy on maternal and neonatal outcomes in Africa: an AFREhealth call for evidence through multicountry research collaboration. The American Journal of Tropical Medicine and Hygiene, 104(2), 461.en_US
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/1596
dc.language.isoenen_US
dc.publisherThe American Journal of Tropical Medicine and Hygieneen_US
dc.titleEffect of SARS-CoV-2 Infection in Pregnancy on Maternal and Neonatal Outcomes in Africa: An AFREhealth Call for Evidence through Multicountry Research Collaborationen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Effect of SARS-CoV-2 Infection in Pregnancy on Maternal and Neonatal Outcomes in Africa An AFREhealth Call for Evidence through Multicountry Research Collaboration.pdf
Size:
300.46 KB
Format:
Adobe Portable Document Format
Description:
Effect of SARS-CoV-2 Infection in Pregnancy on Maternal and Neonatal Outcomes in Africa: An AFREhealth Call for Evidence through Multicountry Research Collaboration
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medical and Health Sciences