Effects and factors associated with indoor residual spraying with Actellic 300 CS on malaria morbidity in Lira District, Northern Uganda

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dc.contributor.authorTugume, Abdulaziz
dc.contributor.authorMuneza, Fiston
dc.contributor.authorOporia, Frederick
dc.contributor.authorKiconco, Arthur
dc.contributor.authorKihembo, Christine
dc.contributor.authorNakanwagi Kisakye, Angela
dc.contributor.authorNsubuga, Peter
dc.contributor.authorSekimpi, Deogratias
dc.contributor.authorYeka, Adoke
dc.date.accessioned2022-03-03T05:59:21Z
dc.date.available2022-03-03T05:59:21Z
dc.date.issued2019
dc.description.abstractIndoor residual spraying (IRS) with Actellic 300 CS was conducted in Lira District between July and August 2016. No formal assessment has been conducted to estimate the effect of spraying with Actellic 300 CS on malaria morbidity in the Ugandan settings. This study assessed malaria morbidity trends before and after IRS with Actellic 300 CS in Lira District in Northern Uganda. Methods: The study employed a mixed methods design. Malaria morbidity records from four health facilities were reviewed, focusing on 6 months before and after the IRS intervention. The outcome of interest was malaria morbidity defined as; proportion of outpatient attendance due to total malaria, proportion of outpatient attendance due to confirmed malaria and proportion of malaria case numbers confirmed by microscopy or rapid diagnostic test. Since malaria morbidity was based on count data, an ordinary Poisson regression model was used to obtain percentage point change (pp) in monthly malaria cases before and after IRS. A household survey was also conducted in 159 households to determine IRS coverage and factors associated with spraying. A modified Poisson regression model was fitted to determine factors associated with household spray status. Results: The proportion of outpatient attendance due to malaria dropped from 18.7% before spraying to 15.1% after IRS. The proportion of outpatient attendance due to confirmed malaria also dropped from 5.1% before spraying to 4.0% after the IRS intervention. There was a decreasing trend in malaria test positivity rate (TPR) for every unit increase in month after spraying. The decreasing trend in TPR was more prominent 5–6 months after the IRS intervention (Adj. pp = − 0.60, P-value = 0.015; Adj. pp = − 1.19, P-value < 0.001). The IRS coverage was estimated at 89.3%. Households of respondents who were formally employed or owned any form of business were more likely to be unsprayed; (APR = 5.81, CI 2.72–12.68); (APR = 3.84, CI 1.20–12.31), respectivelyen_US
dc.identifier.citationTugume, A., Muneza, F., Oporia, F., Kiconco, A., Kihembo, C., Kisakye, A. N., ... & Yeka, A. (2019). Effects and factors associated with indoor residual spraying with Actellic 300 CS on malaria morbidity in Lira District, Northern Uganda. Malaria Journal, 18(1), 1-10.https://doi.org/10.1186/s12936-019-2681-6en_US
dc.identifier.urihttps://doi.org/10.1186/s12936-019-2681-6
dc.identifier.urihttps://nru.uncst.go.ug/xmlui/handle/123456789/2424
dc.language.isoenen_US
dc.publisherMalaria Journalen_US
dc.subjectMalariaen_US
dc.subjectIndoor residual spraying (IRS)en_US
dc.subjectMorbidity trendsen_US
dc.subjectPercentage point (pp)en_US
dc.subjectTest positivity rate (TPR)en_US
dc.titleEffects and factors associated with indoor residual spraying with Actellic 300 CS on malaria morbidity in Lira District, Northern Ugandaen_US
dc.typeArticleen_US
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